Cyclodextrin

Cyclodextrin (CAS 12619-70-4) is a family of cyclic oligosaccharides produced from starch by enzymatic conversion. Also marketed as Celdex, Ringdex P, and Rhodocap L 20.

Where is Cyclodextrin used?

• Food manufacturing: encapsulating flavors, vitamins and sensitive ingredients to extend shelf life and protect against heat or oxidation
• Pharmaceuticals: improving solubility and bioavailability of poorly water-soluble actives in oral, topical and injectable dosage forms
• Biotechnology: excipients in protein stabilization and tools for cholesterol removal in cell culture media
• Flavor houses apply them for delivery, providing controlled-release taste profiles in confectionery, beverages and functional foods.

Good to know: Beta-cyclodextrin is the most commercially prevalent type; hydroxypropyl beta-cyclodextrin is a chemically modified derivative stocked where enhanced aqueous solubility is required.

Commercial specifications

• Alpha, beta and gamma variants