Solvents
REACH
Cyclohexane
CAS Number
110-82-7
EC Number
203-806-2
What is Cyclohexane?
Cyclohexane (CAS 110-82-7) is a cyclic hydrocarbon solvent used in pharmaceutical manufacturing, industrial cleaning, and chemical synthesis.
Where is Cyclohexane used?
- Pharmaceutical and fine chemical manufacturing: recrystallization solvent and reaction medium
- Active ingredient synthesis where residual solvent profiles must meet strict regulatory limits
- Industrial cleaning: degreasing precision components and removing hydrocarbon-based contaminants from metal surfaces
- Flavor and fragrance: extraction solvent for natural raw materials, isolating aromatic compounds
- Chemical production: feedstock and process solvent in nylon intermediate production
- It is utilized in the oxidation pathway to adipic acid and caprolactam.
Good to know: It delivers strong non-polar solvency with low water miscibility, making it a preferred extraction and reaction medium where aromatic solvents are restricted.
Commercial specifications
- Clear liquid in drum, IBC, and bulk tanker quantities
- High-purity material for specialized use
Other Names (Synonyms)
Hexahydro-Benzene|Benzene hexahydride|Benzene, hexahydro-
What are the physical properties of Cyclohexane?
Melting Point 6.47 °C
Boiling Point 80.7 °C @ Press: 760 Torr
Density 0.7781 g/cm³ @ Temp: 20 °C
Flash Point -1 °F
Appearance colorless liquid
Color colorless
Odor resembling benzene; mild, sweet, resembling chloroform.
Form Liquid
Water Solubility PRACTICALLY INSOLUBLE
Vapor Pressure 168.8 mm Hg ( 37.7 °C)
Refractive Index n 20/D 1.426(lit.)
Log P 3.44 at 20℃
How is Cyclohexane classified and handled safely? Learn More
Danger
GHS02· Flammable GHS07· Irritant GHS08· Health Hazard GHS09· Environmental Hazard
Hazard Statements
H225 Highly Flammable liquid and vapor
H304 May be fatal if swallowed and enters airways
H305 May be harmful if swallowed and enters airways
H315 Causes skin irritation
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
Which trade and regulatory codes apply to Cyclohexane?
HS Code 29021100
UN Number 1145
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 2