1-bromohexane

CAS Number
111-25-1
EC Number
203-850-2

What is 1-bromohexane?

1-Bromohexane (CAS 111-25-1), also known as hexyl bromide, is a straight-chain alkyl bromide used as a reactive intermediate in organic synthesis.

Where is 1-bromohexane used?

  • Pharmaceutical synthesis: N- or O-alkylation of active pharmaceutical intermediates for drug development
  • Polymer chemistry: functionalizing monomers and modifying backbone structures, influencing solubility and processing behavior in specialty plastics
  • Quaternary ammonium compounds: reacts with tertiary amines to yield surfactants
  • Fragrance and flavor manufacturing: precursor in synthesizing hexyl esters and ethers
  • It functions primarily as an alkylating agent, introducing the hexyl chain into target molecules.

Commercial specifications

  • Drum and IBC quantities
  • Smaller packaging options for laboratory and pilot-scale procurement
  • Technical grade standard; high-purity grades available
  • Purity documentation including GC analysis and COA

Other Names (Synonyms)

hexyl bromide|n-Hexyl bromide|1-Hexyl bromide|Hexane, 1-bromo-|WVA0FAX7GA

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What are the physical properties of 1-bromohexane?

Melting Point -84.7 °C
Boiling Point 158 °C
Density 1.16 g/cm³
Flash Point 135 °F
Appearance colourless liquid
Color Clear
Form Liquid
Water Solubility Immiscible with water.
Vapor Pressure <10 mm Hg ( 20 °C)
Refractive Index n 20/D 1.448(lit.)

How is 1-bromohexane classified and handled safely? Learn More

Warning
GHS02· Flammable GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H226 Flammable liquid and vapor
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Which trade and regulatory codes apply to 1-bromohexane?

HS Code 29033036
UN Number 1993
ADR Class 3
Packing Group III
Storage Class 3 - Flammable liquids
WGK (Germany) 2
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