Hydrogen bromide

CAS Number
10035-10-6
EC Number
233-113-0
Chemical Formula
BrH
Molecular Weight
80.91 g/mol
Abbreviation
HBr

Description

Hydrogen bromide (CAS 10035-10-6), commercially supplied as hydrobromic acid in aqueous solution, is an inorganic acid used across pharmaceutical synthesis, food processing, and water treatment. HBr delivers strong acidification and bromide ion activity that drive its utility across multiple industrial sectors. In pharmaceutical manufacturing, hydrobromic acid is used to produce active pharmaceutical ingredient salts.

Hydrobromide salts improve the stability and solubility profile of amine-based drug compounds, making them suitable for solid dosage formulation. Water treatment operations use HBr as a bromination precursor. It reacts with oxidants to generate hypobromous acid for microbiological control in cooling towers and process water systems. In food-grade applications, it functions as a pH-regulating agent in controlled processing environments.

Catalyst systems in organic synthesis also rely on HBr as a brominating agent for producing intermediates used in agrochemicals and specialty chemicals. Hydrobromic acid is supplied as an aqueous solution. The 48% concentration is the most commercially standard grade. Both technical and reagent-grade specifications are available, with pharmaceutical-grade material produced to USP and Ph. Eur. standards.

These quality benchmarks ensure suitability for API salt formation. Packaging ranges from drums and IBCs to bulk tanker supply depending on the specific volume requirements of the industrial facility.

Other Names (Synonyms)

HBr|HYDROBROMIC ACID|Acido bromidrico|bromane|Acide bromhydrique|Hydrogen bromide (HBr)|Anhydrous hydrobromic acid|Hydrogen bromide (H2Br2)

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
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Physical Properties

Melting Point -87 °C
Boiling Point -67 °C
Density 1.8 g/cm³
Flash Point 40°C
Appearance colourless liquid with a strong irritating odour
Color Light yellow, brown
Odor Sharp, irritating odor detectable at 2 ppm
Form Solution
Water Solubility soluble
Vapor Pressure 334.7 psi ( 21 °C)
Refractive Index n 20/D 1.438
pH 3.01(1 mM solution);2.04(10 mM solution);1.08(100 mM solution)
Log P 0.629 at 25℃

Documentation

Safety & Handling Learn More

Danger
GHS04· Compressed Gas GHS05· Corrosive GHS07· Irritant GHS06· Toxic GHS08· Health Hazard

Hazard Statements

H280 H280
H314 H314
H318 H318
H331 H331

Precautionary Statements

P260 P260
P261 P261
P264 P264
P270 P270

Trade & Regulatory

HS Code 28111990
UN Number 3265
ADR Class 8
Packing Group II
Storage Class 8B - Non-combustible corrosive hazardous materials
WGK (Germany) 1
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