Hydrogen iodide

Hydrogen iodide (CAS 10034-85-2), commercially known as hydroiodic acid, is an inorganic acid used primarily as a reducing agent and iodine source in chemical synthesis.

Where is Hydrogen iodide used?

• Pharmaceutical synthesis: reagent for dealkylation reactions, particularly in the production of active pharmaceutical ingredients
• Methyl ether cleavage for complex molecules
• Biotechnology and life sciences: reagent in nucleotide chemistry and iodination protocols for labeling and analytical workflows
• Industrial pH adjustment draws on its strong acid character.

Good to know: In aqueous solution, it delivers both strong acid activity and iodide ion availability; this is useful where iodide co-introduction is acceptable or required for the final product.

Commercial specifications

• Aqueous solution, 47% and 57% w/w concentrations
• Stabilized grades include a hypophosphorous acid additive to prevent oxidation and maintain product clarity during long-term storage and transport