Hydroxylamine hydrochloride

CAS Number
5470-11-1
EC Number
226-798-2

What is Hydroxylamine hydrochloride?

Hydroxylamine hydrochloride (CAS 5470-11-1), also known as hydroxylammonium chloride, is a stable, water-soluble salt form of hydroxylamine.

Where is Hydroxylamine hydrochloride used?

  • Pharmaceutical synthesis: converts ketones and aldehydes into oximes, a step in producing active pharmaceutical ingredients and intermediates
  • Polymer chemistry: antioxidant stabilizer and polymerization inhibitor controlling degradation in nylon and engineering plastics
  • Biotechnology: selective protein-cleaving reagent for Asn-Gly bond cleavage in peptide mapping
  • Analytical chemistry: metal ion detection and reducing agent in sample preparation
  • It also acts as a reducing agent, oxime-forming reagent and chemical intermediate in multi-step synthesis.

Commercial specifications

  • Purity typically 98% or higher depending on grade
  • Packaging from small laboratory quantities to bulk industrial volumes

Other Names (Synonyms)

Hydroxylammonium chloride|Oxammonium hydrochloride|Hydroxyamine hydrochloride|Hydroxylamine chloride (1:1)|5X4ZA62Z4Q|HYDROXYLAMINE CHLOROHYDRATE|RefChem:5895

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What are the physical properties of Hydroxylamine hydrochloride?

Melting Point 151 °C (decomp)
Density 1.7 g/cm³
Appearance White crystals
Color White to off-white
Form Liquid
Water Solubility 560 g/L (20 ºC)
Vapor Pressure 0.054 Pa (50 °C)
pH 2.5-3.5 (25℃, 50mg/mL in H2O)
Log P -0.810 (est)

How is Hydroxylamine hydrochloride classified and handled safely? Learn More

Warning
GHS05· Corrosive GHS07· Irritant GHS08· Health Hazard GHS09· Environmental Hazard GHS06· Toxic

Hazard Statements

H290 May be corrosive to metals
H301 Toxic if swallowed
H302 Harmful if swallowed
H312 Harmful in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P234 Keep only in original packaging.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

Which trade and regulatory codes apply to Hydroxylamine hydrochloride?

HS Code 28251000
UN Number 2923
ADR Class 8
Packing Group II
Storage Class 4.1A - Other explosive hazardous materials
WGK (Germany) 3
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