Glycine hydrochloride

Glycine hydrochloride (CAS 6000-43-7), also known as aminoacetic acid hydrochloride, is the hydrochloride salt form of glycine used across pharmaceutical, food, and personal care manufacturing. It functions primarily as a pH buffer and acidulant in formulations where precise, stable acidic conditions are required. In pharmaceutical manufacturing, it serves as a buffering agent in parenteral formulations.

This material is essential for lyophilized drug products and API synthesis where controlled pH is critical to product stability. Food and nutrition producers use it to adjust acidity in functional food systems. It also acts as a preservation aid where mild antimicrobial activity is needed at low pH. Personal care formulators incorporate it into skin-conditioning products to support moisture retention.

Its hygroscopic character is beneficial in both leave-on and rinse-off formats. It also appears in peptide synthesis workflows as a protected amino acid precursor for specialty chemical and biotech procurement. The product is supplied as a white crystalline powder. Pharmaceutical-grade material is available to USP and BP specifications, supporting regulated drug product manufacturing requirements.

Technical and reagent grades are also commercially available for industrial synthesis and laboratory applications. This ensures versatility across various industrial sectors and research environments globally.