Glucosamine hydrochloride

Glucosamine hydrochloride (CAS 66-84-2), also known as Glucosamine HCl, is an amino monosaccharide salt derived primarily from shellfish chitin or produced via microbial fermentation.

Where is Glucosamine hydrochloride used?

• Pharmaceutical and nutraceutical: active ingredient in OTC joint health products and intermediate in synthesis of complex compounds
• Dietary supplements: preferred form for tablet and capsule formulations due to higher nitrogen content and lower molecular weight than the sulfate salt, allowing more active substance per dose
• Functional food and beverage: incorporated into fortified products positioned for mobility and joint wellness
• Cosmetics: moisturizing creams and serums, where it supports skin barrier function and acts as a humectant in leave-on formulations.

Good to know: Both shellfish-derived and non-shellfish (fermentation-based) origins are commercially available, an important distinction for allergen-sensitive supply chains and specialized product lines.