Glucosamine
Description
Glucosamine (CAS 3416-24-8), also known as D-glucosamine, is an amino monosaccharide derived from chitin that serves as a foundational building block in pharmaceutical synthesis and nutraceutical manufacturing.
It functions as a precursor to glycosaminoglycans and is a primary active ingredient in joint health formulations sold globally. In nutraceuticals and dietary supplements, it is the active compound in joint support products.
These products target cartilage maintenance and are often combined with chondroitin or MSM. Pharmaceutical manufacturers use it as an intermediate in synthesizing more complex glycoconjugates and as a starting material for drug development.
In cosmetic formulations, it acts as a humectant and skin-conditioning agent in anti-aging creams and serums. Its moisture-retention profile supports product performance claims in high-end skincare applications.
Food-grade applications include functional food enrichment targeting mobility and joint wellness in aging consumer demographics. Glucosamine is commercially available as a white crystalline powder in its free base form.
The hydrochloride and sulfate salt forms are more common in finished product manufacturing. Standard grades include USP, BP, and food-grade specifications to meet regulatory requirements across global supply chains.
These standards ensure compliance across pharmaceutical, supplement, and cosmetic industries. Bulk supply is typically offered in kilogram to metric ton quantities, with documentation supporting GMP-compliant sourcing.
Physical Properties
| Melting Point | 88 °C |
| Boiling Point | 311.69°C (rough estimate) |
| Density | 1.3767 (rough estimate) |
| Appearance | (β form.) Colorless needles. Mp 110C (decomposes). Very soluble in water; slightly soluble in methanol and ethanol; insoluble in ether and chloroform. |
| Color | White to Off-White |
| Form | Solid |
| Refractive Index | 1.4240 (estimate) |
| Log P | -2.175 (est) |
Documentation
Other Names
2-Amino-2-deoxy-D-glucose|D-glucosamine|2-amino-2-deoxy-D-glucopyranose|(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol|Mediflex|GlcN|2-Deoxy-2-amino-D-glucose|D-GlcN
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