Glycylglycine

Glycylglycine (CAS 556-50-3), also known as Gly-Gly and glycine dipeptide, is the simplest naturally occurring dipeptide, composed of two glycine residues. It functions primarily as a biological buffer and humectant across pharmaceutical and personal care applications. In pharmaceutical formulations, Gly-Gly is used as a buffering agent to maintain stable pH in injectable solutions, protein therapeutics, and lyophilized drug products where precise pH control is critical to product stability.

Cosmetic formulators incorporate it into moisturizing serums, creams, and toners for its ability to attract and retain moisture at the skin surface. It also serves as a reference standard and reagent in biochemical research and peptide synthesis workflows. In cell culture media and enzyme assay systems, it is used to maintain physiological pH without interfering with biological activity. Glycylglycine is supplied as a white crystalline powder available in reagent-grade and pharmaceutical-grade specifications.

High-purity lots supporting GMP-compliant manufacturing ensure the highest quality for sensitive applications. Bulk quantities are offered alongside smaller research-scale packaging to serve both industrial formulators and laboratory procurement needs. Our material meets rigorous internal quality controls to ensure consistency across batches. This dipeptide is an essential component for developers requiring reliable buffering capacity and high solubility in aqueous systems.