2-bromopropane

CAS Number
75-26-3
EC Number
200-855-1

What is 2-bromopropane?

2-Bromopropane (CAS 75-26-3), commercially known as isopropyl bromide, is an alkyl halide used as a reactive intermediate in organic synthesis and as a specialty solvent in industrial processing.

Where is 2-bromopropane used?

  • Pharmaceutical synthesis: key building block for active pharmaceutical ingredients and intermediates requiring selective isopropylation
  • Agrochemicals: synthesis of herbicide and pesticide compounds
  • Plastics and polymer chemistry: flame retardant formulations and specialty polymer modifications
  • Textile and leather processing: solvent and chemical intermediate in dyeing auxiliaries and pigment-related formulations
  • It functions as an alkylating agent, introducing isopropyl groups into target molecules.

Good to know: Controlled alkylation determines the efficacy profile of the final active ingredient in agricultural applications. Buyers should confirm purity specifications and stabilizer content when sourcing for sensitive synthesis processes.

Commercial specifications

  • Standard packaging includes drums and intermediate bulk containers
  • High-purity grades available for pharmaceutical intermediate applications

Other Names (Synonyms)

ISOPROPYL BROMIDE|Propane, 2-bromo-|sec-Propyl bromide|R651XOV97Z

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What are the physical properties of 2-bromopropane?

Melting Point -89.0 °C
Boiling Point 59.38 °C @ Press: 760 Torr
Density 1.31 g/cm³ @ Temp: 20 °C
Flash Point 67 °F
Appearance colourless liquid
Color Clear colorless to very light brown
Form Liquid
Water Solubility 0.3 g/100 mL
Vapor Pressure 224 hPa (20 °C)
Refractive Index n 20/D 1.425(lit.)

How is 2-bromopropane classified and handled safely? Learn More

Danger
GHS02· Flammable GHS08· Health Hazard

Hazard Statements

H225 Highly Flammable liquid and vapor
H316 Causes mild skin irritation
H320 Causes eye irritation
H350 May cause cancer

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.

Which trade and regulatory codes apply to 2-bromopropane?

HS Code 29033036
UN Number 2344
ADR Class 3
Packing Group II
WGK (Germany) 1
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