Solvents
REACH
1,2,3-trichloropropane
CAS Number
96-18-4
EC Number
202-486-1
What is 1,2,3-trichloropropane?
1,2,3-Trichloropropane (CAS 96-18-4), also known as glyceryl trichlorohydrin and allyl trichloride, is a chlorinated solvent and chemical intermediate.
Where is 1,2,3-trichloropropane used?
- Pharmaceutical manufacturing: intermediate in synthesis of active ingredients requiring halogenated carbon frameworks
- Agrochemicals: precursor in preparation of pesticide and herbicide compounds
- Polymer chemistry: production of epichlorohydrin-derived resins and specialty polymers
- Fine chemical production: solvent properties support extraction and reaction processes where chlorinated media are specified
- It functions as a reactive solvent and building block in multi-step synthesis.
Good to know: Buyers sourcing for pharmaceutical intermediate use should confirm lot-specific purity documentation and impurity profiles.
Commercial specifications
- Purity levels typically specified at 98% or higher depending on intended synthesis application
- Liquid in bulk quantities and intermediate packaging such as drums and IBCs
Other Names (Synonyms)
glyceryl trichlorohydrin|glycerol trichlorohydrin|allyl trichloride|TCP|Propane, 1,2,3-trichloro-|NCI-C60220
What are the physical properties of 1,2,3-trichloropropane?
Melting Point -14.7 °C
Boiling Point 156.85 °C
Density 1.3889 g/cm³ @ Temp: 20 °C
Flash Point 180 °F
Appearance Colorless liquid. Slightly soluble in water; dissolves oils, fats, waxes, chlorinated rubber, and numerous resins. autoign temp 580F (304C). Combustible.
Color Colorless to Almost colorless
Form neat
Water Solubility 2 g/L (25 ºC)
Vapor Pressure 3.1 at 25 °C (Banerjee et al., 1990)
Refractive Index n 20/D 1.484(lit.)
Log P 2.63 at 25℃
How is 1,2,3-trichloropropane classified and handled safely? Learn More
Danger
GHS07· Irritant GHS08· Health Hazard GHS06· Toxic GHS09· Environmental Hazard
Hazard Statements
H227 Combustible liquid
H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
Which trade and regulatory codes apply to 1,2,3-trichloropropane?
HS Code 29031980
UN Number 2810
ADR Class 6.1
Packing Group III
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
WGK (Germany) 3