1,2,3-trichloropropane
Description
1,2,3-Trichloropropane (CAS 96-18-4), also known as glyceryl trichlorohydrin and allyl trichloride, is a chlorinated solvent and chemical intermediate used across pharmaceutical, agrochemical, and polymer manufacturing.
It functions primarily as a reactive solvent and building block in multi-step synthesis processes. In pharmaceutical manufacturing, it serves as an intermediate in the synthesis of active ingredients requiring halogenated carbon frameworks.
Agrochemical producers use it as a precursor in the preparation of certain pesticide and herbicide compounds. In polymer chemistry, it contributes to the production of epichlorohydrin-derived resins and specialty polymers.
These applications often require trifunctional chlorinated intermediates to achieve specific chemical structures. Its solvent properties also support extraction and reaction processes in fine chemical production where chlorinated media are specified.
The compound is supplied as a liquid in bulk quantities and intermediate packaging such as drums and IBCs. Technical grade is the standard commercial offering for most industrial and manufacturing requirements.
Purity levels are typically specified at 98% or higher depending on the intended synthesis application. Buyers sourcing for pharmaceutical intermediate use should confirm lot-specific purity documentation and impurity profiles.
Ensuring consistent quality standards is essential for maintaining the integrity of the final chemical products. Suppliers provide detailed technical data sheets to assist in the integration of this material into existing workflows.
Physical Properties
| Melting Point | -14.7 °C |
| Boiling Point | 156.85 °C |
| Density | 1.3889 g/cm³ @ Temp: 20 °C |
| Flash Point | 180 °F |
| Appearance | Colorless liquid. Slightly soluble in water; dissolves oils, fats, waxes, chlorinated rubber, and numerous resins. autoign temp 580F (304C). Combustible. |
| Color | Colorless to Almost colorless |
| Form | neat |
| Water Solubility | 2 g/L (25 ºC) |
| Vapor Pressure | 3.1 at 25 °C (Banerjee et al., 1990) |
| Refractive Index | n 20/D 1.484(lit.) |
| Log P | 2.63 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29031980 |
| UN Number | 2810 |
| ADR Class | 6.1 |
| Packing Group | III |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 3 |
Documentation
Other Names
glyceryl trichlorohydrin|glycerol trichlorohydrin|allyl trichloride|TCP|Propane, 1,2,3-trichloro-|NCI-C60220
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