SoleChem

1,2,3-trichloropropane

CAS
96-18-4
EC
202-486-1
Mol. Weight
147.43 g/mol

Description

1,2,3-Trichloropropane (CAS 96-18-4), also known as glyceryl trichlorohydrin and allyl trichloride, is a chlorinated solvent and chemical intermediate used across pharmaceutical, agrochemical, and polymer manufacturing.

It functions primarily as a reactive solvent and building block in multi-step synthesis processes. In pharmaceutical manufacturing, it serves as an intermediate in the synthesis of active ingredients requiring halogenated carbon frameworks.

Agrochemical producers use it as a precursor in the preparation of certain pesticide and herbicide compounds. In polymer chemistry, it contributes to the production of epichlorohydrin-derived resins and specialty polymers.

These applications often require trifunctional chlorinated intermediates to achieve specific chemical structures. Its solvent properties also support extraction and reaction processes in fine chemical production where chlorinated media are specified.

The compound is supplied as a liquid in bulk quantities and intermediate packaging such as drums and IBCs. Technical grade is the standard commercial offering for most industrial and manufacturing requirements.

Purity levels are typically specified at 98% or higher depending on the intended synthesis application. Buyers sourcing for pharmaceutical intermediate use should confirm lot-specific purity documentation and impurity profiles.

Ensuring consistent quality standards is essential for maintaining the integrity of the final chemical products. Suppliers provide detailed technical data sheets to assist in the integration of this material into existing workflows.

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Physical Properties

Melting Point -14.7 °C
Boiling Point 156.85 °C
Density 1.3889 g/cm³ @ Temp: 20 °C
Flash Point 180 °F
Appearance Colorless liquid. Slightly soluble in water; dissolves oils, fats, waxes, chlorinated rubber, and numerous resins. autoign temp 580F (304C). Combustible.
Color Colorless to Almost colorless
Form neat
Water Solubility 2 g/L (25 ºC)
Vapor Pressure 3.1 at 25 °C (Banerjee et al., 1990)
Refractive Index n 20/D 1.484(lit.)
Log P 2.63 at 25℃

Safety & Handling (Learn More)

Danger GHS07 GHS08 GHS06 GHS09
Hazard Statements
H227 Combustible liquid
H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin
H319 Causes serious eye irritation
H330 Fatal if inhaled
H331 Toxic if inhaled
H332 Harmful if inhaled
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
H341 Suspected of causing genetic defects
H350 May cause cancer
H360 May damage fertility or the unborn child
H370 Causes damage to organs
H371 May cause damage to organs
H372 Causes damage to organs through prolonged or repeated exposure
H373 May causes damage to organs through prolonged or repeated exposure
H401 Toxic to aquatic life
H411 Toxic to aquatic life with long lasting effects
H301+H311 Toxic if swallowed or in contact with skin
H301+H311+H331 Toxic if swallowed, in contact with skin or if inhaled
H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 In case of inadequate ventilation wear respiratory protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P320 Specific treatment is urgent (see … on this label).
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P391 Collect spillage.
P403 Store in a well-ventilated place.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P316 Get emergency medical help immediately.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P308+P316 Get emergency medical help immediately.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P362+P364 Take off contaminated clothing and wash it before reuse.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29031980
UN Number 2810
ADR Class 6.1
Packing Group III
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3

Documentation

Other Names

glyceryl trichlorohydrin|glycerol trichlorohydrin|allyl trichloride|TCP|Propane, 1,2,3-trichloro-|NCI-C60220

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