1,2,3-trichloropropane

CAS Number
96-18-4
EC Number
202-486-1
Chemical Formula
C3H5Cl3
Molecular Weight
147.43 g/mol

Description

1,2,3-Trichloropropane (CAS 96-18-4), also known as glyceryl trichlorohydrin and allyl trichloride, is a chlorinated solvent and chemical intermediate used across pharmaceutical, agrochemical, and polymer manufacturing. It functions primarily as a reactive solvent and building block in multi-step synthesis processes. In pharmaceutical manufacturing, it serves as an intermediate in the synthesis of active ingredients requiring halogenated carbon frameworks.

Agrochemical producers use it as a precursor in the preparation of certain pesticide and herbicide compounds. In polymer chemistry, it contributes to the production of epichlorohydrin-derived resins and specialty polymers. These applications often require trifunctional chlorinated intermediates to achieve specific chemical structures. Its solvent properties also support extraction and reaction processes in fine chemical production where chlorinated media are specified.

The compound is supplied as a liquid in bulk quantities and intermediate packaging such as drums and IBCs. Technical grade is the standard commercial offering for most industrial and manufacturing requirements. Purity levels are typically specified at 98% or higher depending on the intended synthesis application. Buyers sourcing for pharmaceutical intermediate use should confirm lot-specific purity documentation and impurity profiles.

Ensuring consistent quality standards is essential for maintaining the integrity of the final chemical products. Suppliers provide detailed technical data sheets to assist in the integration of this material into existing workflows.

Other Names (Synonyms)

glyceryl trichlorohydrin|glycerol trichlorohydrin|allyl trichloride|TCP|Propane, 1,2,3-trichloro-|NCI-C60220

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -14.7 °C
Boiling Point 156.85 °C
Density 1.3889 g/cm³ @ Temp: 20 °C
Flash Point 180 °F
Appearance Colorless liquid. Slightly soluble in water; dissolves oils, fats, waxes, chlorinated rubber, and numerous resins. autoign temp 580F (304C). Combustible.
Color Colorless to Almost colorless
Form neat
Water Solubility 2 g/L (25 ºC)
Vapor Pressure 3.1 at 25 °C (Banerjee et al., 1990)
Refractive Index n 20/D 1.484(lit.)
Log P 2.63 at 25℃

Documentation

Safety & Handling Learn More

Danger
GHS07· Irritant GHS08· Health Hazard GHS06· Toxic GHS09· Environmental Hazard

Hazard Statements

H227 Combustible liquid
H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

Trade & Regulatory

HS Code 29031980
UN Number 2810
ADR Class 6.1
Packing Group III
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3
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