2-Adamantanamine hydrochloride

CAS Number
10523-68-9
EC Number
234-074-2

What is 2-Adamantanamine hydrochloride?

2-Adamantanamine hydrochloride (CAS 10523-68-9), also known as 2-Aminoadamantane hydrochloride, is a bridged-ring amine salt used as a building block in pharmaceutical synthesis.

Where is 2-Adamantanamine hydrochloride used?

  • Pharmaceutical synthesis: key intermediate for CNS-active drugs
  • Drug design: rigid adamantane scaffold for metabolic stability and receptor selectivity
  • Antiviral and antidiabetic development: scaffold construction for DPP-4 inhibitors
  • Ion channel modulation
  • Medicinal chemistry: SAR studies on bridged ring effects on pharmacokinetic profiles
  • Biotech research: coupling partner for labeled probes and receptor binding assay conjugates

Commercial specifications

  • CoA, HPLC purity data and residual solvent profiles aligned with ICH guidelines
  • Research quantities through to multi-kilogram lots

Other Names (Synonyms)

2-Aminoadamantane hydrochloride|RefChem:85017|adamantan-2-amine hydrochloride|2-Adamantylamine hydrochloride|2-Adamantanamine HCl|Tricyclo[3.3.1.13,7]decan-2-amine, hydrochloride (1:1)|Tricyclo[3.3.1.13,7]decan-2-amine, hydrochloride

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What are the physical properties of 2-Adamantanamine hydrochloride?

Melting Point 300-325 °C (decomp)
Appearance white crystalline powder
Color White
Form Crystalline Powder
Water Solubility soluble

How is 2-Adamantanamine hydrochloride classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to 2-Adamantanamine hydrochloride?

HS Code 29213000
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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