2-amino-5-chlorobenzotrifluoride
Description
2-Amino-5-chlorobenzotrifluoride (CAS 445-03-4), also known as 2-Trifluoromethyl-4-chloroaniline, is an aromatic amine intermediate built around a trifluoromethyl group and a reactive primary amine. It serves as a key building block in the synthesis of active pharmaceutical ingredients, agrochemicals, and specialty dyes. In pharmaceutical manufacturing, it is used to construct drug candidates and APIs.
The trifluoromethyl group is required to improve metabolic stability and membrane permeability. Dye and pigment producers use it as a coupling component or precursor in the synthesis of azo colorants. These colorants are used for textile and paper applications. Its biocidal profile supports use in formulations targeting preservation applications within personal care and cosmetic products.
The compound also appears in agrochemical synthesis, where fluorinated aniline scaffolds are used to build herbicide and fungicide active substances. It is supplied as a liquid or low-melting solid. This depends on purity and handling conditions. It is available in technical and high-purity grades suited to pharmaceutical intermediate and fine chemical manufacturing requirements.
Packaging options typically range from small laboratory quantities through to bulk drums for industrial-scale procurement. This ensures flexibility for various production scales and research needs.
Other Names (Synonyms)
4-Chloro-alpha,alpha,alpha-trifluoro-o-toluidine|Benzenamine, 4-chloro-2-(trifluoromethyl)-|2-Trifluoromethyl-4-chloroaniline|RefChem:561881|4-Chloro-2-(trifluoromethyl)aniline|o-Toluidine, 4-chloro-α,α,α-trifluoro-|4-Chloro-2-(trifluoromethyl)benzenamine|C.I. 37055
Key Technical Features
- High Purity Grade standard
- Consistent Batch Quality
- Full Regulatory & REACH Support
- Global Logistics Network enabled