2-Chloro-5-(trifluoromethyl)aniline
Description
2-Chloro-5-(trifluoromethyl)aniline (CAS 121-50-6), also known commercially as 3-Amino-4-chlorobenzotrifluoride or Fast Orange Salt RD, is an aromatic amine building block used across dye chemistry and agrochemical synthesis.
Its halogenated and trifluoromethyl-substituted structure makes it a targeted intermediate for constructing complex active molecules in pharmaceutical manufacturing. In the textile and leather industries, it functions as a diazonium coupling component.
This chemical is used to produce azo dyes with strong color fastness on fiber substrates. Agrochemical formulators use it as a key intermediate in synthesizing herbicides and fungicides where the trifluoromethyl group contributes to biological activity.
The trifluoromethyl group also provides metabolic stability in various applications. Pharmaceutical manufacturers incorporate it into API synthesis routes, particularly for compounds requiring a halogenated aniline scaffold for efficacy.
In coatings and adhesive systems, it supports the development of specialty resins and crosslinked polymer matrices with targeted performance profiles. This versatile chemical is supplied as a liquid or low-melting solid for industrial use.
It is typically available in technical and synthesis grades to meet diverse manufacturing requirements. It is available in packaging ranging from laboratory quantities to bulk drums for large-scale industrial procurement needs.
Purity specifications commonly range from 98% to 99%+ by GC, with documentation supporting pharmaceutical and agrochemical intermediate applications. Quality control ensures consistency across all batches for high-performance results.
Physical Properties
| Melting Point | 10 °C |
| Boiling Point | 57-58 °C @ Press: 1.5 Torr |
| Density | 1.428 g/mL at 25 °C(lit.) |
| Flash Point | 75 °C |
| Appearance | CLEAR COLORLESS TO LIGHT YELLOW LIQUID |
| Color | Colorless to Yellow to Green |
| Form | clear liquid |
| Water Solubility | 11 g/L (60 ºC) |
| Vapor Pressure | 0.15 hPa |
| Refractive Index | n 20/D 1.499(lit.) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29214300 |
| UN Number | 2810 |
| ADR Class | 6.1 |
| Packing Group | III |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 2 |
Documentation
Other Names
3-Amino-4-chlorobenzotrifluoride|Benzenamine, 2-chloro-5-(trifluoromethyl)-|Fast Orange Salt RD|Orange Salt NRD|Daito Orange Salt RD|Diazo Fast Orange RD|Fast Orange Salt RDA|Fast Orange Salt RDN
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