Pigments & Colorants
REACH
2-Chloro-5-(trifluoromethyl)aniline
CAS Number
121-50-6
EC Number
204-475-7
What is 2-Chloro-5-(trifluoromethyl)aniline?
2-Chloro-5-(trifluoromethyl)aniline (CAS 121-50-6) is an aromatic amine building block used in dye chemistry and agrochemical synthesis. Also marketed as 3-Amino-4-chlorobenzotrifluoride or Fast Orange Salt RD.
Where is 2-Chloro-5-(trifluoromethyl)aniline used?
- Pharmaceutical manufacturing: intermediate for complex active molecules, incorporated into API synthesis routes requiring a halogenated aniline scaffold
- Textile and leather: diazonium coupling component
- Azo dyes with strong color fastness on fiber substrates
- Agrochemicals: key intermediate in herbicides and fungicides, where the trifluoromethyl group contributes to biological activity
- Coatings and adhesives: specialty resins and crosslinked polymer matrices
- The trifluoromethyl group also provides metabolic stability.
Commercial specifications
- Purity 98% to 99%+ by GC
- Documentation supporting pharmaceutical and agrochemical intermediate applications
- Packaging from laboratory quantities to bulk drums
Other Names (Synonyms)
3-Amino-4-chlorobenzotrifluoride|Benzenamine, 2-chloro-5-(trifluoromethyl)-|Fast Orange Salt RD|Orange Salt NRD|Daito Orange Salt RD|Diazo Fast Orange RD|Fast Orange Salt RDA|Fast Orange Salt RDN
What are the physical properties of 2-Chloro-5-(trifluoromethyl)aniline?
Melting Point 10 °C
Boiling Point 57-58 °C @ Press: 1.5 Torr
Density 1.428 g/mL at 25 °C(lit.)
Flash Point 75 °C
Appearance CLEAR COLORLESS TO LIGHT YELLOW LIQUID
Color Colorless to Yellow to Green
Form clear liquid
Water Solubility 11 g/L (60 ºC)
Vapor Pressure 0.15 hPa
Refractive Index n 20/D 1.499(lit.)
How is 2-Chloro-5-(trifluoromethyl)aniline classified and handled safely? Learn More
Warning
GHS07· Irritant GHS09· Environmental Hazard
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H411 Toxic to aquatic life with long lasting effects
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
Which trade and regulatory codes apply to 2-Chloro-5-(trifluoromethyl)aniline?
HS Code 29214300
UN Number 2810
ADR Class 6.1
Packing Group III
Storage Class 10 - Combustible liquids
WGK (Germany) 2