SoleChem

2-Chloro-5-(trifluoromethyl)aniline

CAS
121-50-6
EC
204-475-7
Mol. Weight
195.57 g/mol

Description

2-Chloro-5-(trifluoromethyl)aniline (CAS 121-50-6), also known commercially as 3-Amino-4-chlorobenzotrifluoride or Fast Orange Salt RD, is an aromatic amine building block used across dye chemistry and agrochemical synthesis.

Its halogenated and trifluoromethyl-substituted structure makes it a targeted intermediate for constructing complex active molecules in pharmaceutical manufacturing. In the textile and leather industries, it functions as a diazonium coupling component.

This chemical is used to produce azo dyes with strong color fastness on fiber substrates. Agrochemical formulators use it as a key intermediate in synthesizing herbicides and fungicides where the trifluoromethyl group contributes to biological activity.

The trifluoromethyl group also provides metabolic stability in various applications. Pharmaceutical manufacturers incorporate it into API synthesis routes, particularly for compounds requiring a halogenated aniline scaffold for efficacy.

In coatings and adhesive systems, it supports the development of specialty resins and crosslinked polymer matrices with targeted performance profiles. This versatile chemical is supplied as a liquid or low-melting solid for industrial use.

It is typically available in technical and synthesis grades to meet diverse manufacturing requirements. It is available in packaging ranging from laboratory quantities to bulk drums for large-scale industrial procurement needs.

Purity specifications commonly range from 98% to 99%+ by GC, with documentation supporting pharmaceutical and agrochemical intermediate applications. Quality control ensures consistency across all batches for high-performance results.

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Physical Properties

Melting Point 10 °C
Boiling Point 57-58 °C @ Press: 1.5 Torr
Density 1.428 g/mL at 25 °C(lit.)
Flash Point 75 °C
Appearance CLEAR COLORLESS TO LIGHT YELLOW LIQUID
Color Colorless to Yellow to Green
Form clear liquid
Water Solubility 11 g/L (60 ºC)
Vapor Pressure 0.15 hPa
Refractive Index n 20/D 1.499(lit.)

Safety & Handling (Learn More)

Warning GHS07 GHS09
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H411 Toxic to aquatic life with long lasting effects
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29214300
UN Number 2810
ADR Class 6.1
Packing Group III
Storage Class 10 - Combustible liquids
WGK (Germany) 2

Documentation

Other Names

3-Amino-4-chlorobenzotrifluoride|Benzenamine, 2-chloro-5-(trifluoromethyl)-|Fast Orange Salt RD|Orange Salt NRD|Daito Orange Salt RD|Diazo Fast Orange RD|Fast Orange Salt RDA|Fast Orange Salt RDN

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