Memantine hydrochloride
What is Memantine hydrochloride?
Memantine hydrochloride (CAS 41100-52-1) is the salt form of memantine, an NMDA receptor antagonist active pharmaceutical ingredient used in the treatment of moderate-to-severe Alzheimer's disease.
Where is Memantine hydrochloride used?
- Generic pharmaceutical manufacturers: active ingredient in immediate-release and extended-release tablet formulations for cognitive decline disorders
- Contract development organizations: reference standard or bulk API for bioequivalence studies and formulation development
- Compounding pharmacies: documented API for patient-specific preparations
- Research institutions source pharmaceutical-grade material for investigational use.
Good to know: Standard supply grades include USP, EP (Ph. Eur.), and in-house pharmaceutical grades with full ICH-compliant documentation packages for regulatory submission. Certificates of Analysis, DMF references, and impurity profiles are standard documentation expectations in regulated markets.
Commercial specifications
- Bulk quantities from laboratory-scale to commercial API lots
- ICH-compliant documentation packages
Other Names (Synonyms)
memantine.HCl|3,5-dimethyltricyclo(3.3.1.1(3,7))decan-1-amine hydrochloride|3,5-dimethyladamantan-1-aminium chloride|3,5-Dimethyl-1-adamantanamine hydrochloride|1-Amino-3,5-dimethyladamantane hydrochloride|3,5-dimethyladamantan-1-amine hydrochloride|Akatinol|Namenda XR