Memantine hydrochloride

Memantine hydrochloride (CAS 41100-52-1) is the salt form of memantine, an NMDA receptor antagonist active pharmaceutical ingredient used in the treatment of moderate-to-severe Alzheimer's disease.

Supplied as a finished API or pharmaceutical intermediate, it is a primary target for generic drug manufacturers and contract formulators sourcing for solid oral dosage development.

Generic pharmaceutical manufacturers use this material as the active ingredient in immediate-release and extended-release tablet formulations indicated for cognitive decline disorders.

Contract development organizations source it as a reference standard or bulk API for bioequivalence studies and formulation development against branded products in the marketplace.

It is also procured by compounding pharmacies requiring a documented API for patient-specific preparations. Research institutions source pharmaceutical-grade material for investigational use.

Memantine hydrochloride is available as a white crystalline powder in bulk quantities ranging from laboratory-scale to commercial API lots for global distribution and manufacturing.

Standard supply grades include USP, EP (Ph. Eur.), and in-house pharmaceutical grades with full ICH-compliant documentation packages for regulatory submission.

Certificates of Analysis, DMF references, and impurity profiles are standard documentation expectations for this material in regulated markets to ensure safety and compliance.