Quinine hydrochloride

Quinine hydrochloride (CAS 130-89-2), also known as Quinine HCl, is the salt form of quinine derived from cinchona bark alkaloids.

Where is Quinine hydrochloride used?

• Pharmaceutical manufacturing: active ingredient and intermediate
• Oral and injectable dosage development: water-soluble form preferred over quinine base
• Tablets, capsules, and injectable solutions for malaria treatment and fever management
• Food and beverage: bittering agent in tonic waters and carbonated soft drinks under FEMA 2976
• Topical and oral formulations for nocturnal leg cramp management in select regulated markets
• Compounding pharmacies use it as a starting material for customized dosage forms requiring defined quinine salt concentrations.

Good to know: Its water solubility makes it the preferred form over quinine base for oral and injectable dosage development. Precise dosing controls the characteristic bitter taste profile required for beverages.

Commercial specifications

• Standard grades: USP, BP, Ph. Eur.
• Bulk quantities for industrial buyers and R&D customers