Quinine sulfate

CAS Number
804-63-7
EC Number
212-359-1
Chemical Formula
C20H24N2O2.1/2H2O4S
Molecular Weight
746.9 g/mol
FEMA Number
FEMA 2977

Description

Quinine sulfate (CAS 804-63-7) is the sulfate salt form of quinine, also marketed as quinine sulphate, used primarily in pharmaceutical manufacturing and analytical research. Supplied as a stable, water-soluble solid, it offers reliable handling and consistent purity for regulated production environments. In pharmaceutical manufacturing, this compound serves as the active ingredient in oral dosage forms targeting nocturnal leg cramps and malaria treatment in regulated markets. Analytical and QC laboratories use it as a fluorescence standard for calibrating spectrophotometers.

The material is essential for validating UV detection systems, given its well-characterized emission profile. In the food and beverage industry, it functions as a bittering agent in tonic waters and carbonated drinks under FEMA 2977. Precise dosing is required to meet regulatory bitterness thresholds in commercial beverage production. Biotechnology researchers also use it in cell biology assays and as a reference compound in pharmacokinetic studies for drug development.

Quinine sulfate is available as a white to off-white crystalline powder in both anhydrous and dihydrate forms. Standard grades include USP, BP, and Ph. Eur., supporting use in GMP-regulated pharmaceutical production. Research and reagent-grade material is also available for laboratory and analytical applications. These high-purity options ensure consistent results across various industrial and scientific workflows while meeting strict international quality benchmarks.

Other Names (Synonyms)

quinine sulphate|Quinine sulfate anhydrous|Quinine sulfate (2:1)|Quinine hydrogen sulfate|Quinine bisulfate|M4XCR57IWG|Qualaquin|Coco-Quinine

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 235.2 °C
Density 1.0807 (rough estimate)
Color White to off-white
Odor wh. fine needle-like cryst., odorless, very bitter taste
Form Solid
Refractive Index 1.6000 (estimate)
Log P 3.44

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 H302
H315 H315
H317 H317
H319 H319
H335 H335

Precautionary Statements

P261 P261
P264 P264
P270 P270
P271 P271

Trade & Regulatory

HS Code 29339900
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