Chloroquine

Chloroquine (CAS 54-05-7) is a synthetic 4-aminoquinoline compound established as a reference pharmaceutical active ingredient and research chemical. It serves as a primary building block and analytical reference standard in drug development.

Supplied as the base or phosphate salt form, it is essential for manufacturing workflows. Pharmaceutical manufacturers use it as an active pharmaceutical ingredient in the production of finished dosage forms.

These forms primarily include tablets and oral solutions targeting parasitic indications. Research institutions and contract development organizations source it as a reference standard for analytical method validation.

It is also utilized for bioequivalence studies and pharmacokinetic assays. In drug discovery programs, it functions as a scaffold compound for synthesizing novel quinoline-based derivatives under investigation.

Formulators working on generic drug development use it as a comparator substance. This application is critical during formulation optimization and stability testing protocols to ensure product efficacy and safety.

The material is available as a free base or, more commonly, as Chloroquine phosphate. This is the predominant commercial salt form used in finished pharmaceutical production across the global industry.

Standard grades include USP, BP, and Ph.Eur. specifications for compliance. Research-grade material is also supplied for non-GMP laboratory applications and experimental chemical synthesis.

Packaging ranges from small quantities for reference use to bulk quantities supporting commercial API manufacturing. This flexibility ensures that both laboratory and industrial requirements are met efficiently.