Amines REACH

Cinchonine

CAS Number
118-10-5
EC Number
204-234-6
Chemical Formula
C19H22N2O
Molecular Weight
294.4 g/mol

Description

Cinchonine (CAS 118-10-5) is a natural cinchona bark alkaloid used across pharmaceutical, biotechnology, and personal care sectors. Commercially recognized as D-Cinchonine, it functions primarily as a chiral resolving agent. It serves as a biochemical tool compound in synthesis and research workflows. In pharmaceutical manufacturing, it resolves racemic mixtures to isolate enantiomerically pure active ingredients for production.

This is a critical step in API production where chiral purity directly affects regulatory approval. Biotechnology researchers use it as a reference standard and chiral selector in chromatographic method development. Personal care formulators incorporate it into preservation systems where alkaloid-based antimicrobial activity supports product stability. It also serves research applications in asymmetric catalysis for development.

Its quinuclidine-quinoline scaffold is used to develop organocatalyst systems. The material is supplied as a white to off-white crystalline powder available in reagent-grade and high-purity specifications. It is suited to pharmaceutical and analytical applications, with select suppliers offering material compliant with reference standard requirements. Packaging ranges from small research quantities to bulk orders.

Industrial-scale chiral resolution processes utilize this compound for its reliable performance. The product meets rigorous industry expectations for consistency and chemical stability in various environments.

Other Names (Synonyms)

D-Cinchonine|(9S)-Cinchonan-9-ol|Cinchonan-9-ol, (9S)-|(8R,9S)-Cinchonine|(+)-Cinconine|V43X79NZCD|Cinchonine Alkaloid

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 265 °C
Boiling Point 436.16°C (rough estimate)
Density 1.0863 (rough estimate)
Appearance white to light yellow crystal powde
Color White to light beige
Form Micro-Crystalline Powder
Water Solubility Insoluble
Vapor Pressure 0Pa at 25℃
Refractive Index 223 ° (C=0.5, EtOH)
pH 9.0 (0.25g/l, H2O, 20℃)(as aqueous solution)
Log P 2.82 at 25℃

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 H302
H317 H317
H332 H332

Precautionary Statements

P261 P261
P264 P264
P270 P270
P271 P271

Trade & Regulatory

HS Code 29339900
WGK (Germany) 3
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