SoleChem

Cinchonine

CAS
118-10-5
EC
204-234-6
Mol. Weight
294.4 g/mol

Description

Cinchonine (CAS 118-10-5) is a natural cinchona bark alkaloid used across pharmaceutical, biotechnology, and personal care sectors. Commercially recognized as D-Cinchonine, it functions primarily as a chiral resolving agent.

It serves as a biochemical tool compound in synthesis and research workflows. In pharmaceutical manufacturing, it resolves racemic mixtures to isolate enantiomerically pure active ingredients for production.

This is a critical step in API production where chiral purity directly affects regulatory approval. Biotechnology researchers use it as a reference standard and chiral selector in chromatographic method development.

Personal care formulators incorporate it into preservation systems where alkaloid-based antimicrobial activity supports product stability. It also serves research applications in asymmetric catalysis for development.

Its quinuclidine-quinoline scaffold is used to develop organocatalyst systems. The material is supplied as a white to off-white crystalline powder available in reagent-grade and high-purity specifications.

It is suited to pharmaceutical and analytical applications, with select suppliers offering material compliant with reference standard requirements. Packaging ranges from small research quantities to bulk orders.

Industrial-scale chiral resolution processes utilize this compound for its reliable performance. The product meets rigorous industry expectations for consistency and chemical stability in various environments.

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Physical Properties

Melting Point 265 °C
Boiling Point 436.16°C (rough estimate)
Density 1.0863 (rough estimate)
Appearance white to light yellow crystal powde
Color White to light beige
Form Micro-Crystalline Powder
Water Solubility Insoluble
Vapor Pressure 0Pa at 25℃
Refractive Index 223 ° (C=0.5, EtOH)
pH 9.0 (0.25g/l, H2O, 20℃)(as aqueous solution)
Log P 2.82 at 25℃

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 H302
H317 H317
H332 H332
Precautionary Statements
P261 P261
P264 P264
P270 P270
P271 P271
P272 P272
P280 P280
P317 P317
P321 P321
P330 P330
P501 P501
P301+P317 P301+P317
P302+P352 P302+P352
P304+P340 P304+P340
P333+P317 P333+P317
P362+P364 P362+P364

Trade & Regulatory

HS Code 29339900
WGK (Germany) 3

Documentation

Other Names

D-Cinchonine|(9S)-Cinchonan-9-ol|Cinchonan-9-ol, (9S)-|(8R,9S)-Cinchonine|(+)-Cinconine|V43X79NZCD|Cinchonine Alkaloid

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