Amines REACH

Cinchonine

CAS Number
118-10-5
EC Number
204-234-6

What is Cinchonine?

Cinchonine (CAS 118-10-5) is a natural cinchona bark alkaloid. Also marketed as D-Cinchonine.

Where is Cinchonine used?

  • Pharmaceutical manufacturing: resolves racemic mixtures to isolate enantiomerically pure active ingredients
  • Biotechnology: reference standard and chiral selector in chromatographic method development
  • Personal care: preservation systems where alkaloid-based antimicrobial activity supports product stability
  • Research: biochemical tool compound in synthesis and research workflows
  • Asymmetric catalysis: quinuclidine-quinoline scaffold used to develop organocatalyst systems
  • Industrial-scale chiral resolution processes utilize this compound.

Good to know: Chiral purity directly affects regulatory approval in API production. Select suppliers offer material compliant with reference standard requirements.

Commercial specifications

  • Reagent-grade and high-purity specifications
  • Packaging from small research quantities to bulk orders

Other Names (Synonyms)

D-Cinchonine|(9S)-Cinchonan-9-ol|Cinchonan-9-ol, (9S)-|(8R,9S)-Cinchonine|(+)-Cinconine|V43X79NZCD|Cinchonine Alkaloid

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What are the physical properties of Cinchonine?

Melting Point 265 °C
Boiling Point 436.16°C (rough estimate)
Density 1.0863 (rough estimate)
Appearance white to light yellow crystal powde
Color White to light beige
Form Micro-Crystalline Powder
Water Solubility Insoluble
Vapor Pressure 0Pa at 25℃
Refractive Index 223 ° (C=0.5, EtOH)
pH 9.0 (0.25g/l, H2O, 20℃)(as aqueous solution)
Log P 2.82 at 25℃

How is Cinchonine classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 H302
H317 H317
H332 H332

Precautionary Statements

P261 P261
P264 P264
P270 P270
P271 P271

Which trade and regulatory codes apply to Cinchonine?

HS Code 29339900
WGK (Germany) 3
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