3-Bromoquinoline
CAS Number
5332-24-1
EC Number
226-237-1
What is 3-Bromoquinoline?
3-Bromoquinoline (CAS 5332-24-1) is a halogenated heterocyclic building block used primarily in pharmaceutical synthesis and specialty chemical manufacturing.
Where is 3-Bromoquinoline used?
- Pharmaceutical development: key intermediate for active pharmaceutical ingredients and drug candidates
- Polymer and plastics: brominated quinoline derivatives in flame retardant formulations
- Textile and paper treatment: precursor to preservation and stabilization compounds
- Research and fine chemicals: ligands, dyes and specialty reagents from a functionalized quinoline core
- The bromine substituent at the 3-position makes it a reactive intermediate for cross-coupling reactions.
Commercial specifications
- Purity typically 97% or higher
- Technical and high-purity grades
- Packaging from small R&D quantities to bulk industrial-scale synthesis
Other Names (Synonyms)
Quinoline, 3-bromo-|AI3-16560|RefChem:93267|Quinolin-3-yl bromide|DI-SEC-BUTYLAMINE
What are the physical properties of 3-Bromoquinoline?
Melting Point 13.3 °C
Boiling Point 103-105 °C @ Press: 1.5 Torr
Density 1.533 g/mL at 25 °C(lit.)
Flash Point >230 °F
Appearance colorless to light yellow liquid
Color Clear colorless to yellow
Form Liquid
Water Solubility 103mg/L at 25℃
Vapor Pressure 0.196Pa at 25℃
Refractive Index n 20/D 1.664(lit.)
Log P 3.03
How is 3-Bromoquinoline classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Which trade and regulatory codes apply to 3-Bromoquinoline?
HS Code 29334900
UN Number 2810
Storage Class 10 - Combustible liquids
WGK (Germany) 3