1-bromo-4-iodobenzene

CAS Number
589-87-7
EC Number
209-662-7

What is 1-bromo-4-iodobenzene?

1-Bromo-4-iodobenzene (CAS 589-87-7), also known as p-bromoiodobenzene, is a dual-halogenated aromatic building block used in pharmaceutical synthesis and specialty chemical manufacturing.

Where is 1-bromo-4-iodobenzene used?

  • Pharmaceutical intermediates: precursor in palladium-catalyzed reactions exploiting the differential reactivity of bromine and iodine for regioselective functionalization
  • Polymer and materials: introduction of halogenated aryl units into flame-retardant polymer systems with controlled halogen loading
  • Dyes and pigments: reactive intermediate for brominated and iodinated aromatic colorants in textile and leather applications
  • Specialty monomers and cross-linkers for advanced polymer formulations target specific thermal or electronic performance profiles.

Good to know: The two distinct halogen substituents on the benzene ring allow selective cross-coupling reactions.

Commercial specifications

  • Purity typically 98% to 99%+ for fine chemical synthesis
  • Technical and high-purity grades
  • Packaging from small laboratory quantities up to multi-kilogram lots

Other Names (Synonyms)

p-Bromoiodobenzene|Benzene, 1-bromo-4-iodo-|4-bromo-1-iodobenzene|4-iodobromobenzene|4-bromophenyl iodide|4-iodo-1-bromobenzene|R9LDG2XS7C

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What are the physical properties of 1-bromo-4-iodobenzene?

Melting Point 92 °C
Boiling Point 90 °C
Density 2.2236 (rough estimate)
Flash Point 120-122°C/14mm
Appearance white to brown cryst. powder, crystals or needles
Color White to brown
Form Crystalline Powder, Crystals or Needles
Water Solubility Insoluble in water.
Refractive Index 1.6618 (estimate)

How is 1-bromo-4-iodobenzene classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H413 May cause long lasting harmful effects to aquatic life

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.

Which trade and regulatory codes apply to 1-bromo-4-iodobenzene?

HS Code 29036990
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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