SoleChem

1-bromo-4-iodobenzene

CAS
589-87-7
EC
209-662-7
Mol. Weight
282.90 g/mol

Description

1-Bromo-4-iodobenzene (CAS 589-87-7), also known as p-bromoiodobenzene, is a dual-halogenated aromatic building block used across pharmaceutical synthesis and specialty chemical manufacturing.

The presence of two distinct halogen substituents on the benzene ring allows selective cross-coupling reactions, making it a practical starting material for constructing complex molecular architectures.

In pharmaceutical intermediate synthesis, it serves as a key precursor in palladium-catalyzed reactions where chemists exploit the differential reactivity of bromine and iodine to achieve regioselective functionalization.

Polymer and materials chemists use it to introduce halogenated aryl units into flame-retardant polymer systems, particularly where controlled halogen loading is required for specific industrial applications.

In dye and pigment manufacturing, it functions as a reactive intermediate for producing brominated and iodinated aromatic colorants used in various textile and leather applications across the globe.

It also supports the development of specialty monomers and cross-linkers in advanced polymer formulations targeting specific thermal or electronic performance profiles for high-tech manufacturing sectors.

1-Bromo-4-iodobenzene is supplied as a white to off-white crystalline solid. It is available in technical and high-purity grades, with purity levels typically ranging from 98% to 99%+ for fine chemical synthesis.

Packaging options generally range from small laboratory quantities up to multi-kilogram lots for industrial procurement, ensuring reliable supply chains for both research and large-scale production needs.

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Physical Properties

Melting Point 92 °C
Boiling Point 90 °C
Density 2.2236 (rough estimate)
Flash Point 120-122°C/14mm
Appearance white to brown cryst. powder, crystals or needles
Color White to brown
Form Crystalline Powder, Crystals or Needles
Water Solubility Insoluble in water.
Refractive Index 1.6618 (estimate)

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H413 May cause long lasting harmful effects to aquatic life
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29036990
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

p-Bromoiodobenzene|Benzene, 1-bromo-4-iodo-|4-bromo-1-iodobenzene|4-iodobromobenzene|4-bromophenyl iodide|4-iodo-1-bromobenzene|R9LDG2XS7C

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