1-bromo-4-iodobenzene
Description
1-Bromo-4-iodobenzene (CAS 589-87-7), also known as p-bromoiodobenzene, is a dual-halogenated aromatic building block used across pharmaceutical synthesis and specialty chemical manufacturing.
The presence of two distinct halogen substituents on the benzene ring allows selective cross-coupling reactions, making it a practical starting material for constructing complex molecular architectures.
In pharmaceutical intermediate synthesis, it serves as a key precursor in palladium-catalyzed reactions where chemists exploit the differential reactivity of bromine and iodine to achieve regioselective functionalization.
Polymer and materials chemists use it to introduce halogenated aryl units into flame-retardant polymer systems, particularly where controlled halogen loading is required for specific industrial applications.
In dye and pigment manufacturing, it functions as a reactive intermediate for producing brominated and iodinated aromatic colorants used in various textile and leather applications across the globe.
It also supports the development of specialty monomers and cross-linkers in advanced polymer formulations targeting specific thermal or electronic performance profiles for high-tech manufacturing sectors.
1-Bromo-4-iodobenzene is supplied as a white to off-white crystalline solid. It is available in technical and high-purity grades, with purity levels typically ranging from 98% to 99%+ for fine chemical synthesis.
Packaging options generally range from small laboratory quantities up to multi-kilogram lots for industrial procurement, ensuring reliable supply chains for both research and large-scale production needs.
Physical Properties
| Melting Point | 92 °C |
| Boiling Point | 90 °C |
| Density | 2.2236 (rough estimate) |
| Flash Point | 120-122°C/14mm |
| Appearance | white to brown cryst. powder, crystals or needles |
| Color | White to brown |
| Form | Crystalline Powder, Crystals or Needles |
| Water Solubility | Insoluble in water. |
| Refractive Index | 1.6618 (estimate) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29036990 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
p-Bromoiodobenzene|Benzene, 1-bromo-4-iodo-|4-bromo-1-iodobenzene|4-iodobromobenzene|4-bromophenyl iodide|4-iodo-1-bromobenzene|R9LDG2XS7C
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