4-bromo-1,8-naphthalic anhydride

CAS Number
81-86-7
EC Number
201-382-3

What is 4-bromo-1,8-naphthalic anhydride?

4-Bromo-1,8-naphthalic anhydride (CAS 81-86-7) is a halogenated cyclic anhydride used as a reactive intermediate in the synthesis of naphthalimide-based dyes, fluorescent pigments, and specialty polymers.

Where is 4-bromo-1,8-naphthalic anhydride used?

  • Textile and printing: precursor to high-performance fluorescent dyes for fabric brightening and inkjet colorants
  • Polymer chemistry: incorporated into polyimide backbones with controlled optical or electronic properties
  • Pharmaceutical intermediates: synthesis of bioactive candidates
  • Specialty pigments: production of vat dyes
  • Solvent dyes for plastics coloration and packaging inks
  • The naphthalimide scaffold is elaborated through palladium-catalyzed cross-coupling or nucleophilic substitution at the bromine site.

Good to know: The bromine substituent provides a handle for further functionalization.

Commercial specifications

  • Purity specifications commonly ranging from 97% to 99%+ depending on the intended application and specific requirements
  • Packaging options range from small laboratory quantities to multi-kilogram industrial lots

Other Names (Synonyms)

6-Bromo-1H,3H-naphtho[1,8-cd]pyran-1,3-dione|1H,3H-Naphtho[1,8-cd]pyran-1,3-dione, 6-bromo-|RefChem:437750|Naphthalic anhydride, 4-bromo-|4-Bromonaphthalic anhydride|4-Bromo-1,8-naphthalenedicarboxylic anhydride

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What are the physical properties of 4-bromo-1,8-naphthalic anhydride?

Melting Point 218-220 °C
Boiling Point 467.2±28.0 °C(Predicted)
Density 1.812±0.06 g/cm3(Predicted)
Color Off-White to Pale Yellow
Form Solid

How is 4-bromo-1,8-naphthalic anhydride classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to 4-bromo-1,8-naphthalic anhydride?

HS Code 29173990
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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