4-nitrobenzoic acid
Description
4-Nitrobenzoic acid (CAS 62-23-7), also known as p-Nitrodracylic acid, is an aromatic nitro compound used primarily as a chemical intermediate in pharmaceutical synthesis and dye manufacturing.
It functions as a building block for active pharmaceutical ingredients, azo pigments, and specialty organic compounds requiring a para-substituted benzoic acid backbone for specific chemical reactions.
In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of APIs including local anesthetics, antimicrobials, and cardiovascular compounds during the production process.
Azo dye and pigment producers use it to introduce nitro functionality into colorant structures, influencing hue and lightfastness in various textile and ink applications across the industry.
In organic synthesis, it acts as a pH buffer and mild preservative in formulation systems where controlled acidity and microbial inhibition are both required for product stability.
Personal care formulators have explored it in preservation systems targeting specific microbial strains at low concentrations. The material is supplied as a pale yellow to off-white crystalline powder.
Technical and pharmaceutical-grade material is available, with purity specifications typically ranging from 98% to 99%+ depending on the intended application and the required USP or BP standards.
Packaging options generally span from kilogram-scale laboratory quantities to bulk industrial volumes. This ensures flexibility for both research development and large-scale commercial manufacturing needs.
Physical Properties
| Melting Point | 242 °C |
| Boiling Point | 150 °C @ Press: 0.02 Torr |
| Density | 1.610 g/cm³ @ Temp: 20 °C |
| Flash Point | 237 °C |
| Appearance | light yellow crystalline powder |
| Color | Light yellow |
| Form | Crystalline Powder |
| Water Solubility | <0.1 g/100 mL at 26 ºC |
| Refractive Index | 1.6280 (estimate) |
| pH | 3.1 (0.42g/l, H2O, 20℃)(saturated solution) |
| Log P | 1.890 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29163900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Documentation
Other Names
p-Nitrodracylic acid|p-Nitrobenzoic acid|p-Nitrobenzenecarboxylic acid|Nitrodracylic acid|4-Nitrodracylic acid|1-Carboxy-4-nitrobenzene|Benzoic acid, 4-nitro-|Benzoic acid, p-nitro-
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