4-nitrobenzoic acid

CAS Number
62-23-7
EC Number
200-526-2

What is 4-nitrobenzoic acid?

4-Nitrobenzoic acid (CAS 62-23-7), also known as p-Nitrodracylic acid, is an aromatic nitro compound used primarily as a chemical intermediate in pharmaceutical synthesis and dye manufacturing.

Where is 4-nitrobenzoic acid used?

  • Pharmaceuticals: building block for active pharmaceutical ingredients, including local anesthetics, antimicrobials and cardiovascular compounds
  • Dyes and pigments: introduces nitro functionality into azo colorant structures, influencing hue and lightfastness in textile and ink applications
  • Organic synthesis: pH buffer and mild preservative where controlled acidity and microbial inhibition are required
  • Personal care formulators have explored it in preservation systems targeting specific microbial strains at low concentrations.

Commercial specifications

  • Technical and pharmaceutical grades; purity typically 98% to 99%+, per USP or BP standards
  • Packaging from kilogram-scale laboratory quantities to bulk industrial volumes

Other Names (Synonyms)

p-Nitrodracylic acid|p-Nitrobenzoic acid|p-Nitrobenzenecarboxylic acid|Nitrodracylic acid|4-Nitrodracylic acid|1-Carboxy-4-nitrobenzene|Benzoic acid, 4-nitro-|Benzoic acid, p-nitro-

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What are the physical properties of 4-nitrobenzoic acid?

Melting Point 242 °C
Boiling Point 150 °C @ Press: 0.02 Torr
Density 1.610 g/cm³ @ Temp: 20 °C
Flash Point 237 °C
Appearance light yellow crystalline powder
Color Light yellow
Form Crystalline Powder
Water Solubility <0.1 g/100 mL at 26 ºC
Refractive Index 1.6280 (estimate)
pH 3.1 (0.42g/l, H2O, 20℃)(saturated solution)
Log P 1.890

How is 4-nitrobenzoic acid classified and handled safely? Learn More

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H319 Causes serious eye irritation
H320 Causes eye irritation
H332 Harmful if inhaled

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.

Which trade and regulatory codes apply to 4-nitrobenzoic acid?

HS Code 29163900
Storage Class 11 - Combustible Solids
WGK (Germany) 1
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