SoleChem

Quinine hydrochloride dihydrate

CAS
6119-47-7
EC
205-001-1
Mol. Weight
396.9 g/mol

Description

Quinine hydrochloride dihydrate (CAS 6119-47-7), commonly referenced as Quinine HCl Dihydrate in pharmaceutical procurement, is the water-soluble hydrochloride salt form of quinine supplied in its stable dihydrate state.

It functions as an antimalarial active and bitter-tasting agent across pharmaceutical and personal care manufacturing. In pharmaceutical manufacturing, it serves as an active pharmaceutical ingredient in antimalarial formulations.

Its hydrochloride salt form offers improved aqueous solubility over quinine sulfate for injectable and oral dosage development. Beverage and flavoring applications utilize its intensely bitter profile to standardize bitterness.

It is used in tonic formulations and reference standards. In personal care and cosmetic formulations, it is incorporated into scalp treatments and hair care products targeting hair loss and scalp conditioning.

QA and analytical laboratories source it as a reference standard for UV fluorescence calibration and spectrophotometric method validation. Quinine hydrochloride dihydrate is available as a white to off-white crystalline powder.

It is supplied in pharmaceutical-grade specifications aligned with BP and Ph. Eur. monographs, supporting GMP-compliant manufacturing environments. Packaging ranges from small quantities to bulk quantities.

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Physical Properties

Melting Point 123 °C (approx)
Flash Point 122 °C
Appearance white to light yellow crystal powde
Color White to off-white
Odor odorless
Form Crystalline Powder or Silky Needles
Water Solubility Sparingly soluble in water.(0.26 g/L) (25°C),
Refractive Index -250 ° (C=2, EtOH)
pH 6.0 (10g/l, H2O, 20℃)

Safety & Handling (Learn More)

Warning GHS07 GHS08
Hazard Statements
H302 H302
H317 H317
H332 H332
H334 H334
Precautionary Statements
P233 P233
P260 P260
P261 P261
P264 P264
P270 P270
P271 P271
P272 P272
P280 P280
P284 P284
P317 P317
P321 P321
P330 P330
P403 P403
P501 P501
P301+P317 P301+P317
P302+P352 P302+P352
P304+P340 P304+P340
P333+P317 P333+P317
P342+P316 P342+P316
P362+P364 P362+P364

Trade & Regulatory

HS Code 29334900
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

Quinine HCl Dihydrate|Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, dihydrate, (8a,9R)-|Quinidine Hydrochloride Dihydrate|Cinchonan-9-ol, 6′-methoxy-, hydrochloride, hydrate (1:1:2), (8α,9R)-|Cinchonan-9-ol, 6′-methoxy-, monohydrochloride, dihydrate, (8α,9R)-

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