Quinine hydrochloride dihydrate

Quinine hydrochloride dihydrate (CAS 6119-47-7), commonly referenced as Quinine HCl Dihydrate in pharmaceutical procurement, is the water-soluble hydrochloride salt form of quinine supplied in its stable dihydrate state. It functions as an antimalarial active and bitter-tasting agent across pharmaceutical and personal care manufacturing. In pharmaceutical manufacturing, it serves as an active pharmaceutical ingredient in antimalarial formulations.

Its hydrochloride salt form offers improved aqueous solubility over quinine sulfate for injectable and oral dosage development. Beverage and flavoring applications utilize its intensely bitter profile to standardize bitterness. It is used in tonic formulations and reference standards. In personal care and cosmetic formulations, it is incorporated into scalp treatments and hair care products targeting hair loss and scalp conditioning.

QA and analytical laboratories source it as a reference standard for UV fluorescence calibration and spectrophotometric method validation. Quinine hydrochloride dihydrate is available as a white to off-white crystalline powder. It is supplied in pharmaceutical-grade specifications aligned with BP and Ph. Eur. monographs, supporting GMP-compliant manufacturing environments. Packaging ranges from small quantities to bulk quantities.