Lisinopril dihydrate

Lisinopril dihydrate (CAS 83915-83-7) is the stable, hydrated crystalline form of lisinopril, a lysine-proline derivative used as an active pharmaceutical ingredient in antihypertensive drug manufacturing.

Its dihydrate form is the commercially preferred specification for finished dosage form production, offering consistent physical stability under standard storage conditions for global distribution.

The primary application is in the manufacture of oral solid dosage forms, such as tablets and capsules, targeting hypertension and heart failure treatment where it functions as the API in formulations.

Contract manufacturers and generic drug producers source it as a pharmaceutical intermediate for direct compression or wet granulation processes. It is a staple in modern cardiovascular medicine production.

Formulators working on combination antihypertensive products incorporate it alongside diuretics such as hydrochlorothiazide in fixed-dose tablet formats to improve patient compliance and therapeutic outcomes.

Reference standard quantities are also procured by QA laboratories and analytical teams for method validation and release testing. This ensures the highest level of safety and efficacy in the final product.

Lisinopril dihydrate is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications meeting USP, BP, and Ph. Eur. compendial standards.

These are the primary requirements for API procurement in regulated markets. Packaging is typically offered in small quantities for laboratory use through to bulk quantities for commercial manufacturing.