Clopidogrel bisulfate

Clopidogrel bisulfate (CAS 120202-66-6), also marketed as clopidogrel hydrogen sulfate, is the active pharmaceutical ingredient form of clopidogrel used in the manufacture of antiplatelet medications.

Where is Clopidogrel bisulfate used?

• Generic pharmaceutical manufacturers: API in tablet formulations
• Cardiovascular indications: formulations requiring polymorph control and purity for regulatory submission
• Contract development and manufacturing organizations: starting point for 75 mg oral solid dose products
• Combination cardiovascular products: salt form specified for fixed-dose combinations compatible with standard tablet excipients
• It is the commercially dominant salt form selected for finished dose production.

Good to know: Polymorph Form I is the standard commercially supplied crystalline form. Not to be confused with other salt forms.

Commercial specifications

• Pharmaceutical-grade specifications aligned with USP and EP monograph requirements
• Polymorph Form I
• Packaging from small analytical quantities through multi-kilogram lots to support clinical batch manufacturing
• 75 mg oral solid dose products