Celecoxib

Celecoxib (CAS 169590-42-5), also marketed under the brand name Onsenal®, is a selective COX-2 inhibitor API used as the active pharmaceutical ingredient in prescription anti-inflammatory drug products.

It is sourced by pharmaceutical manufacturers and contract formulators for finished dosage form production. Celecoxib is the primary active ingredient in oral solid dosage forms, principally hard gelatin capsules.

These products are indicated for arthritis and acute pain management. Contract manufacturers source it for inclusion in both branded and generic pharmaceutical products across regulated markets globally.

Its low aqueous solubility drives demand for specialized formulation approaches, including solid dispersions and nanoparticle-based systems. This makes it a reference compound in bioavailability enhancement development.

API suppliers also serve research institutions and analytical laboratories requiring reference-grade material for method validation and comparative studies. Celecoxib is supplied as a white to off-white crystalline powder.

It is available in pharmaceutical-grade specifications conforming to USP and EP monograph standards. Documentation packages include CoA, DMF references, and ICH-compliant impurity profiles.

Bulk quantities are typically offered for commercial manufacturing, with smaller quantities available for R&D and formulation development purposes. This ensures supply chain flexibility for various scales.