Celecoxib

Celecoxib (CAS 169590-42-5), also marketed as Onsenal®, is a selective COX-2 inhibitor API used as the active ingredient in prescription anti-inflammatory drugs.

Where is Celecoxib used?

• Pharmaceutical manufacturing and contract formulation for finished dosage forms
• Primary active ingredient in oral solid dosage forms, principally hard gelatin capsules
• Arthritis and acute pain management
• Branded and generic products in regulated markets
• Low aqueous solubility drives specialized formulation such as solid dispersions and nanoparticle systems
• It serves as a reference compound in bioavailability enhancement development.

Good to know: Its low aqueous solubility drives demand for specialized formulation approaches. API suppliers also serve research institutions and analytical laboratories requiring reference-grade material for method validation and comparative studies.

Commercial specifications

• Pharmaceutical-grade specifications conforming to USP and EP monograph standards
• Documentation: CoA, DMF references, ICH-compliant impurity profiles
• Bulk quantities for commercial manufacturing; smaller quantities for R&D and formulation development