Ciprofloxacin
Description
Ciprofloxacin (CAS 85721-33-1) is a broad-spectrum fluoroquinolone antibiotic active ingredient supplied to pharmaceutical manufacturers under trade names including Ciprobay and Velmonit.
It targets a wide range of gram-negative and gram-positive bacteria, making it a core API in prescription antimicrobial formulations globally for various medical applications.
The primary commercial application is in finished oral and injectable antibiotic drug products, where ciprofloxacin is formulated as tablets, infusion solutions, and extended-release dosage forms.
Ophthalmic and otic preparations represent a distinct formulation category, with ciprofloxacin incorporated into drops and ointments for localized infection treatment in clinical settings.
Veterinary pharmaceutical manufacturers also source ciprofloxacin as an API for animal health products targeting bacterial infections in livestock and companion animals across the globe.
In personal care and cosmetic preservation research, it is evaluated as a biocidal reference compound in antimicrobial efficacy testing protocols to ensure product safety and stability.
Ciprofloxacin is supplied as a white to pale yellow crystalline powder. Standard grades include USP, BP, and Ph. Eur. pharmacopoeial specifications for industrial use.
The hydrochloride salt form is also commercially available to meet specific solubility requirements. Bulk API is typically offered in quantities ranging from laboratory-scale to multi-kilogram lots.
Physical Properties
| Melting Point | 225-257 °C (decomp) |
| Boiling Point | 685.30 °C |
| Density | 1.5 g/cm³ |
| Appearance | White Powder |
| Color | White to Almost white |
| Form | powder |
| Water Solubility | 86mg/L(25 ºC) |
Trade & Regulatory
| HS Code | 29335900 |
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Documentation
Other Names
Velmonit|CPR867|Ciprobay|Cipro|Ciloxan|BAY-Q-3939|1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid|Cipro IV
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