Norfloxacin
Description
Norfloxacin (CAS 70458-96-7) is a second-generation fluoroquinolone antibiotic active ingredient used in pharmaceutical manufacturing. It functions as a broad-spectrum antibacterial agent targeting both gram-positive and gram-negative organisms.
This makes it a core API in finished dosage form production for global markets. In pharmaceutical formulation, it is the active ingredient in oral tablets and suspensions indicated for urinary tract and gastrointestinal bacterial infections.
Ophthalmic and otic preparations incorporate it as the primary antibacterial component in drops and solutions for ocular and ear infections. Contract manufacturers and generic drug producers source it as a pharmaceutical intermediate.
It is frequently used for the synthesis of related fluoroquinolone derivatives in laboratory settings. Topical antimicrobial formulations in the personal care and pharmaceutical space also utilize it for preservation and infection control.
These applications are specific to regulated product categories requiring high-purity ingredients. The product is supplied as a white to pale yellow crystalline powder for industrial use. It is available in pharmaceutical-grade specifications.
These include USP, BP, and Ph. Eur. standards, with purity levels typically at 99% or above to meet API requirements. Bulk quantities are standard for industrial and contract manufacturing procurement.
Smaller research-grade quantities are also available through specialty chemical distributors for testing. This ensures that manufacturers can maintain consistent quality across various production scales and regulatory environments.
Physical Properties
| Melting Point | 227-228 °C |
| Boiling Point | 555.8±50.0 °C(Predicted) |
| Density | 1.2504 (estimate) |
| Appearance | Off-white to light yellow cryst powder |
| Color | White to yellow |
| Form | Crystalline Powder |
| Water Solubility | Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29335900 |
| WGK (Germany) | 2 |
Documentation
Other Names
Quinabic|Noroxin|NFLX|MK-366|Chibroxin|Baccidal|1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid|1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
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