SoleChem

Furosemide

CAS
54-31-9
EC
200-203-6
Mol. Weight
330.74 g/mol

Description

Furosemide (CAS 54-31-9), also known commercially as Lasix, is an active pharmaceutical ingredient (API) in the loop diuretic class. It is used in the manufacture of finished dosage forms targeting fluid retention and edema-related conditions.

This material is utilized across human and veterinary pharmaceutical markets. Furosemide is the primary API in oral tablet formulations, where it is manufactured at standardized strengths for prescription drug products.

Injectable solution manufacturing represents a distinct supply channel, requiring high-purity pharmaceutical-grade material compatible with parenteral processing standards. This ensures safety and efficacy in clinical settings.

Veterinary pharmaceutical producers source this ingredient for companion animal and livestock formulations. It is particularly effective for cardiac and renal indications within the animal health sector.

The compound also serves as a reference standard and analytical reagent in QC laboratories. These facilities use it for validating diuretic drug products and ensuring consistent manufacturing quality.

The product is supplied as a white to off-white crystalline powder. Pharmaceutical-grade material is available to USP, BP, and Ph. Eur. specifications, which are the primary standards required.

Bulk API is typically offered in kilogram and multi-kilogram quantities to meet industrial demand. Documentation packages include CoA, DMF references, and GMP certification to support regulatory submissions.

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Physical Properties

Melting Point 206 °C
Boiling Point 582.1±60.0 °C(Predicted)
Density 1.594 g/cm³ (solid)
Flash Point 11 °C
Appearance white to light yellow crystal powde
Color White to Off-White
Form powder
Water Solubility Soluble in acetone, DMF or methanol. Slightly soluble in water
Refractive Index 1.6580 (estimate)

Safety & Handling (Learn More)

Danger GHS07 GHS08
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H351 Suspected of causing cancer
H360 May damage fertility or the unborn child
H361 Suspected of damaging fertility or the unborn child
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 2935904000
UN Number 1230
ADR Class 3
Packing Group II
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3

Documentation

Other Names

4-chloro-N-furfuryl-5-sulfamoylanthranilic acid|4-chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid|4-chloro-5-sulfamoyl-N-furfuryl-anthranilic acid|2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid|Frusemide|Lasix|Furosemid|Errolon

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