Disopyramide

Disopyramide (CAS 3737-09-5) is an active pharmaceutical ingredient used in the treatment of cardiac arrhythmias.

Where is Disopyramide used?

• Class Ia antiarrhythmic: suppresses abnormal electrical activity in the heart muscle
• Restores and maintains normal sinus rhythm
• Primary API in oral dosage forms, including capsules and extended-release tablets, for ventricular and supraventricular arrhythmias
• Key input for branded and generic antiarrhythmic drug products
• Hypertrophic obstructive cardiomyopathy management: reduces outflow tract obstruction
• Research and reference standard laboratories procure small quantities for analytical method development and pharmacokinetic studies.

Good to know: The phosphate salt form, Disopyramide Phosphate, is the more commonly used variant in finished dosage formulations; it is also available under corresponding pharmacopoeial standards such as EP.