Olanzapine

Olanzapine (CAS 132539-06-1), also referenced in procurement as LY-170053, is an atypical antipsychotic active pharmaceutical ingredient used in the manufacture of finished-dose psychiatric medications.

Where is Olanzapine used?

• Schizophrenia and bipolar disorder treatments: primary API for tablet, orally disintegrating tablet and injectable formulations
• Solid oral dosage: conventional film-coated tablets for long-term psychiatric maintenance therapy
• Orally disintegrating tablets: tightly controlled particle size for dissolution and dose uniformity
• Injectable depot formulations: defined polymorphic form and impurity profiles
• Generic and contract manufacturers source it as an intermediate for bioequivalent products.

Good to know: Orally disintegrating tablet formats require tightly controlled particle size; injectable grades require defined polymorphic form and impurity profiles. ICH-compliant impurity profiling is expected for all batches.

Commercial specifications

• High-purity API for solid oral dosage
• Kilogram and multi-kilogram quantities
• GMP-certified documentation packages