Atorvastatin

Atorvastatin (CAS 134523-00-5), also known by the brand name Lipitor, is a synthetic HMG-CoA reductase inhibitor used as an active pharmaceutical ingredient in prescription cholesterol-lowering medications.

It is one of the most commercially significant statin APIs in global pharmaceutical manufacturing and procurement. Atorvastatin API is the core active ingredient in finished oral solid dosage forms.

Primarily film-coated tablets are manufactured for cardiovascular disease management using this material. Generic drug manufacturers source it to produce bioequivalent formulations requiring strict pharmacokinetic matching.

These formulations must match reference listed drugs. Contract development and manufacturing organizations (CDMOs) use it in formulation development projects targeting lipid-lowering therapeutic categories.

It also appears in combination tablet formulations, paired with antihypertensives such as amlodipine. This requires compatibility evaluation during development to ensure stability and efficacy.

Atorvastatin is supplied as a white to off-white crystalline powder in pharmaceutical-grade form. Standard specifications include USP, BP, and Ph. Eur. grades for global compliance.

Purity is typically at 98% or above as required for API use. Packaging is available in quantities ranging from research-scale to commercial bulk for various manufacturing needs.

Documentation including CoA, DMF references, and impurity profiles are available on request. This ensures full transparency and regulatory support for pharmaceutical procurement teams.