Atorvastatin
CAS Number
134523-00-5
EC Number
806-698-0
What is Atorvastatin?
Atorvastatin (CAS 134523-00-5), also known by the brand name Lipitor, is a synthetic HMG-CoA reductase inhibitor used as an active pharmaceutical ingredient in prescription cholesterol-lowering medications.
Where is Atorvastatin used?
- Finished oral solid dosage forms: core active ingredient
- Film-coated tablets for cardiovascular disease management
- Generic bioequivalent formulations requiring strict pharmacokinetic matching
- Formulation development projects targeting lipid-lowering therapeutic categories
- Combination tablets paired with antihypertensives such as amlodipine
- CDMOs use it in formulation development.
Good to know: Combination products require compatibility evaluation during development to ensure stability and efficacy.
Commercial specifications
- Purity typically 98% or above for API use
- USP, BP, and Ph. Eur. grades
- Packaging from research-scale to commercial bulk
- CoA, DMF references, and impurity profiles on request
Other Names (Synonyms)
LCF872|Cardyl|A0JWA85V8F
What are the physical properties of Atorvastatin?
Melting Point 167.73 °C
Boiling Point 722.2±60.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
Color White to light yellow
Form Solid
How is Atorvastatin classified and handled safely? Learn More
Warning
GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H361 Suspected of damaging fertility or the unborn child
H362 May cause harm to breast-fed children
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy and while nursing.
Which trade and regulatory codes apply to Atorvastatin?
HS Code 35040000
Storage Class 11 - Combustible Solids
WGK (Germany) 3