Tadalafil
CAS Number
171596-29-5
EC Number
687-782-2
Industries: Pharma & Healthcare
What is Tadalafil?
Tadalafil (CAS 171596-29-5), also referenced in development literature as IC351, is a PDE5 inhibitor active pharmaceutical ingredient used in the treatment of erectile dysfunction and pulmonary arterial hypertension.
Where is Tadalafil used?
- Prescription drug manufacturing: film-coated tablets at defined dosage strengths for on-demand and daily-use therapeutic regimens
- Compounding pharmacies: bulk API for customized dosage forms for patients with specific clinical requirements
- Pulmonary arterial hypertension: once-daily oral formulations targeting vascular smooth muscle relaxation and improved blood flow
- Research and analytical laboratories procure it as a reference standard or intermediate for method development and quality control testing.
Commercial specifications
- API-grade quality aligned with USP and EP monograph specifications
- Bulk quantities in kilogram-scale packaging
- Documentation including CoA, impurity profiles, and DMF references
Other Names (Synonyms)
Tadanafil|ICOS 351|IC351|Cialis®|Adcirca®|Tadalafil mylan|Trans-tadalafil
What are the physical properties of Tadalafil?
Melting Point 303.2 °C
Boiling Point 679.1±55.0 °C(Predicted)
Density 1.51±0.1 g/cm3(Predicted)
Flash Point 2°C
Appearance White to Off-White Cyrstalline Solid
Color white to beige
Form powder
How is Tadalafil classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
Which trade and regulatory codes apply to Tadalafil?
HS Code 2934990002
WGK (Germany) 3