Lansoprazole

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Lansoprazole (CAS 103577-45-3), also referenced under development codes AG-1749 and A-65006, and widely recognized by the brand name Prevacid, is a proton pump inhibitor (PPI) active pharmaceutical ingredient.

It is used in the treatment of acid-related gastrointestinal disorders and functions by irreversibly blocking gastric acid secretion, making it a core API in prescription and over-the-counter drug formulations globally.

Lansoprazole is formulated into delayed-release capsules and orally disintegrating tablets targeting conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome.

It is also incorporated into combination therapy regimens for Helicobacter pylori eradication, typically alongside antibiotics and bismuth compounds for effective clinical outcomes in patients.

Generic pharmaceutical manufacturers source it as a bulk API for solid dosage form production across regulated and semi-regulated markets. Contract development and manufacturing organizations utilize it in novel delivery formats.

These formats include enteric-coated pellet systems designed to protect the compound from gastric degradation. Lansoprazole is supplied as a white to off-white crystalline powder in bulk quantities for manufacturing.

It is available in USP, BP, and Ph. Eur. pharmacopoeial grades to meet the regulatory requirements of major markets including the US, EU, and UK. This ensures high quality for global distribution.

Packaging is typically offered in double-polyethylene-lined fiber drums under controlled storage conditions. This ensures the stability and integrity of the pharmaceutical ingredient during long-term transit.