Omeprazole

Omeprazole (CAS 73590-58-6), also marketed under the brand names Losec and Prilosec, is a proton pump inhibitor active pharmaceutical ingredient used in the treatment of acid-related gastrointestinal conditions. As a finished API, it is sourced by pharmaceutical manufacturers and contract formulators for integration into oral solid dosage forms. Omeprazole is the core active in delayed-release capsule and tablet formulations.

These formulations target gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. Formulators working with enteric-coated pellet systems rely on this API to ensure acid-stable delivery to the small intestine. It is also incorporated into combination drug products, such as fixed-dose formulations paired with antibiotics for H. pylori eradication regimens. Veterinary pharmaceutical manufacturers source the material for animal treatments.

Omeprazole is supplied as a white to off-white crystalline powder. Standard grades include USP, BP, and Ph. Eur., with purity specifications typically at 99% or above to meet pharmacopoeial requirements. Suppliers commonly offer the material in quantities ranging from kilogram-scale for development batches to multi-kilogram lots for commercial manufacturing. This ensures a stable supply chain for global pharmaceutical production.