Omeprazole sodium

CAS Number
95510-70-6
EC Number
623-285-9
Chemical Formula
C17H19N3O3S.Na
Molecular Weight
367.4 g/mol

Description

Omeprazole sodium (CAS 95510-70-6) is the sodium salt form of omeprazole, commonly referenced in procurement as Losec Sodium. It functions as a proton pump inhibitor active pharmaceutical ingredient, suppressing gastric acid secretion. This compound serves as the basis for injectable and solid oral dosage formulations. The primary application is in parenteral formulations, where the sodium salt form offers improved aqueous solubility compared to the free base.

This enhanced solubility enables IV and infusion preparations for hospital use. It is also used in the manufacture of enteric-coated tablets and capsules targeting gastroesophageal reflux disease and peptic ulcer treatment. Pharmaceutical manufacturers sourcing this material for generic drug production rely on it as a direct API input requiring full regulatory documentation. It is a critical component for high-volume pharmaceutical manufacturing.

Contract formulators developing combination gastric products may also specify this form when targeting rapid-onset delivery profiles. The material ensures consistency across various therapeutic delivery systems and clinical applications. Omeprazole sodium is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications aligned with USP and BP monograph requirements for API use.

Packaging is typically offered in controlled, moisture-protected formats suited to GMP manufacturing environments. This ensures the stability and integrity of the chemical during long-term storage and international transport.

Other Names (Synonyms)

Losec Sodium|H 168/68 sodium|Omeprazole (as sodium)|KV03YZ6QLW|RefChem:55777|Omeprazole sodium [USAN]|Omeprazole sodium salt

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point >165°C (dec.)
Appearance White or almost white, hygroscopic powder.
Color White to Off-White
Form Solid

Safety & Handling (Learn More)

Danger
GHS07· Irritant GHS08· Health Hazard GHS09· Environmental Hazard

Hazard Statements

H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 In case of inadequate ventilation wear respiratory protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P391 Collect spillage.
P403 Store in a well-ventilated place.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P333+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P342+P316 Get emergency medical help immediately.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Documentation

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