Pantoprazole sodium

Pantoprazole sodium (CAS 138786-67-1), also marketed under the brand name Protonix, is a proton pump inhibitor active pharmaceutical ingredient used in the manufacture of prescription gastrointestinal medications. The anhydrous form is the primary commercially traded specification, distinct from the sesquihydrate salt used in some finished formulations. The API is the active component in oral tablet and intravenous formulations.

Indicated for acid-related gastrointestinal conditions, it is a core procurement target for finished dosage form manufacturers. Generic drug producers source this material as the starting material for enteric-coated tablet production. Acid-resistant coating is critical to bioavailability in these applications. Contract manufacturing organizations handling sterile injectables require high-purity grades to meet parenteral formulation standards for patient safety.

It is also sourced by pharmaceutical reference standard suppliers and QC laboratories for analytical and method validation purposes. Pantoprazole sodium is supplied as a white to off-white crystalline powder. It is available in API-grade specifications conforming to USP, BP, and Ph. Eur. pharmacopoeial standards. Packaging ranges from small quantities for laboratory use to multi-kilogram lots for manufacturing.