Posaconazole
CAS Number
171228-49-2
EC Number
682-747-8
Industries: Pharma & Healthcare
What is Posaconazole?
Posaconazole (CAS 171228-49-2), also referenced in development literature as SCH 56592, is a broad-spectrum triazole antifungal active pharmaceutical ingredient marketed under the brand name Noxafil.
Where is Posaconazole used?
- Pharmaceutical manufacturing: API for finished dosage form production under GMP conditions
- Antifungal therapy: oral suspensions, delayed-release tablets and intravenous solutions for prophylaxis and treatment of invasive fungal infections in immunocompromised patients
- Biotechnology: reference standard for antifungal susceptibility testing
- Contract development organizations use this compound in formulation development targeting improved bioavailability delivery systems and drug interaction studies.
Commercial specifications
- Meets USP and EP requirements
- Quantities from small research lots through commercial-scale API batches
- Documentation packages including CoA, impurity profiles and regulatory support files available upon request
Other Names (Synonyms)
Noxafil|Sch 56592|Schering 56592
What are the physical properties of Posaconazole?
Melting Point 171.00 °C
Boiling Point 850.7±75.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
Flash Point 9°C
Appearance White Solid
Color white to beige
Form powder
How is Posaconazole classified and handled safely? Learn More
Danger
GHS07· Irritant GHS08· Health Hazard GHS09· Environmental Hazard
Hazard Statements
H319 Causes serious eye irritation
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Which trade and regulatory codes apply to Posaconazole?
HS Code 3204.90.0000
UN Number 1230
Packing Group II
WGK (Germany) 3