Salcaprozate sodium

CAS Number
203787-91-1
EC Number
682-351-1

What is Salcaprozate sodium?

Salcaprozate sodium (CAS 203787-91-1), also known by its E-number E414, is a synthetic sodium salt used in pharmaceutical formulations as an absorption enhancer and carrier.

Where is Salcaprozate sodium used?

  • Oral peptide and protein drugs: facilitates gastrointestinal absorption of biologics such as insulin and GLP-1 analogues
  • Other macromolecules with negligible bioavailability
  • Buccal and nasal delivery systems: enhanced mucosal uptake of peptide APIs
  • It improves mucosal permeability of poorly absorbed active pharmaceutical ingredients for oral or transmucosal delivery.

Commercial specifications

  • Documentation supports regulatory submissions for global markets
  • Quantities range from research-scale to commercial bulk

Other Names (Synonyms)

sodium 8-[(2-hydroxybenzoyl)amino]octanoate|E414|1YTW0422YU|SNAC sodium|RefChem:180885|Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, sodium salt (1:1)|Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt|Sodium 8-(salicyloylamino)octanoate

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What are the physical properties of Salcaprozate sodium?

Melting Point 183 - 185°C
Color White to Off-White
Form Solid
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