Esomeprazole sodium

Esomeprazole sodium (CAS 161796-78-7), also referenced as Nexium IV, is the sodium salt form of the S-enantiomer of omeprazole.

Where is Esomeprazole sodium used?

• Intravenous pharmaceutical applications
• Proton pump inhibitor (PPI) active pharmaceutical ingredient (API) suppressing gastric acid secretion for therapeutic formulation use
• Manufacture of injectable formulations for hospital and clinical settings where rapid acid suppression is required when oral administration is not feasible
• Pharmaceutical manufacturers producing IV solutions
• Gastroesophageal reflux disease and stress ulcer prophylaxis in critical care patients
• API for lyophilized powder-for-injection presentations for aqueous parenteral systems
• Generic drug manufacturers targeting regulated markets rely on it as the reference-aligned active for IV PPI product development.

Good to know: The sodium salt form supports specific solubility requirements in these systems. Not to be confused with other PPI actives.

Commercial specifications

• Pharmaceutical-grade specifications aligned with USP and Ph. Eur. monograph requirements
• Small-to-medium quantities suited to API procurement workflows
• Documentation packages support regulatory submissions and compliance with international pharmaceutical standards