Rabeprazole sodium

CAS Number
117976-90-6
EC Number
629-730-3
Chemical Formula
C18H21N3O3S.Na
Molecular Weight
381.4 g/mol

Description

Rabeprazole sodium (CAS 117976-90-6), also marketed under the brand name Aciphex, is a proton pump inhibitor used as an active pharmaceutical ingredient in the treatment of acid-related gastrointestinal disorders. It functions by suppressing gastric acid secretion, making it a key API in finished dosage form manufacturing. Rabeprazole sodium is formulated into enteric-coated tablets and delayed-release capsules.

It is used for the management of conditions such as GERD, peptic ulcers, and Zollinger-Ellison syndrome. Contract manufacturers and generic drug producers source it as a primary API for solid oral dosage forms. The material targets the gastrointestinal therapeutic segment and is also used in combination therapy formulations. It is particularly effective alongside antibiotics for H. pylori eradication regimens.

Pharmaceutical formulators evaluating bioequivalence studies or generic product development will source this material to established reference standards. It is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications, with material typically conforming to USP, BP, or in-house pharmacopoeial standards depending on the supplier requirements.

Packaging is offered in controlled quantities suitable for R&D through to commercial-scale API manufacturing. This ensures stability and compliance for global pharmaceutical supply chains and production.

Other Names (Synonyms)

Sodium rabeprazole|Aciphex|Rabeprazole sodium salt|Rabeprazole na|LY307640 sodium|Idiazole|Aciphex Sprinkle|E-3810 SODIUM

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 140-141 °C (decomp)
Appearance White Crystalline Solid
Color white to beige
Form powder
Water Solubility H2O: 10mg/mL (clear solution)

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Trade & Regulatory

HS Code 2933399090
WGK (Germany) 3
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