Rabeprazole sodium

CAS Number
117976-90-6
EC Number
629-730-3

What is Rabeprazole sodium?

Rabeprazole sodium (CAS 117976-90-6), also marketed as Aciphex, is a proton pump inhibitor used as an active pharmaceutical ingredient for acid-related gastrointestinal disorders.

Where is Rabeprazole sodium used?

  • Gastrointestinal therapeutics: management of GERD, peptic ulcers and Zollinger-Ellison syndrome
  • Combination therapy: H. pylori eradication alongside antibiotics
  • Finished dosage manufacturing: enteric-coated tablets and delayed-release capsules
  • Generic drug producers and contract manufacturers source it as a primary API for solid oral dosage forms.

Good to know: Material typically conforms to USP, BP or in-house pharmacopoeial standards depending on supplier requirements.

Commercial specifications

  • Packaging in controlled quantities from R&D to commercial-scale API manufacturing

Other Names (Synonyms)

Sodium rabeprazole|Aciphex|Rabeprazole sodium salt|Rabeprazole na|LY307640 sodium|Idiazole|Aciphex Sprinkle|E-3810 SODIUM

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What are the physical properties of Rabeprazole sodium?

Melting Point 140-141 °C (decomp)
Appearance White Crystalline Solid
Color white to beige
Form powder
Water Solubility H2O: 10mg/mL (clear solution)

How is Rabeprazole sodium classified and handled safely? Learn More

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Which trade and regulatory codes apply to Rabeprazole sodium?

HS Code 2933399090
WGK (Germany) 3
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