Abacavir sulfate

Abacavir sulfate (CAS 188062-50-2), also referenced in procurement as abacavir hemisulfate or 1592U89 sulfate, is the salt form of abacavir used as the active pharmaceutical ingredient in antiretroviral drug manufacturing.

Where is Abacavir sulfate used?

• Nucleoside reverse transcriptase inhibitor (NRTI) incorporated into finished dosage forms targeting HIV treatment
• Manufacture of oral solid and liquid antiretroviral formulations, including tablets, film-coated tablets, and oral solutions for HIV-1 treatment
• Key API in fixed-dose combination products, co-formulated alongside other antiretroviral agents such as lamivudine and dolutegravir
• Generic pharmaceutical manufacturers source this material for finished dosage form production under regulatory filings including ANDAs and MAAs
• Specialty API distributors supply it to formulators developing pediatric antiretroviral preparations.

Good to know: These oral liquid formats require high-purity, well-characterized material to ensure safety and efficacy. GMP-certified material is required for regulated drug product manufacturing to meet international standards.

Commercial specifications

• Pharmaceutical-grade specifications conforming to USP and BP monographs
• Packaging typically offered in controlled quantities suited to standard API handling protocols