Zidovudine

Zidovudine (CAS 30516-87-1), also known as AZT and marketed as Retrovir®, is an antiretroviral nucleoside analogue used as an active pharmaceutical ingredient in HIV treatment formulations.

Where is Zidovudine used?

• Pharmaceutical industry: API in oral solid and liquid dosage forms such as tablets, capsules and syrups for HIV/AIDS treatment protocols
• Fixed-dose combination products: blended with other antiretrovirals under compatibility assessment
• Combination drug substance synthesis: intermediate subject to regulatory review and quality control
• Research institutions and generic drug developers use it as a reference standard or starting material for bioequivalence and stability studies.

Good to know: It functions as a reverse transcriptase inhibitor, blocking viral replication at the enzymatic level. Not to be confused with other nucleoside analogues.

Commercial specifications

• Quantities from research-scale to commercial bulk
• Full batch documentation for regulated-market buyers