Emtricitabine
CAS Number
143491-57-0
EC Number
604-363-1
Abbreviation
FTC
Industries: Pharma & Healthcare
What is Emtricitabine?
Emtricitabine (CAS 143491-57-0), also known by the development codes BW-524W91 and 524W91 and abbreviated as FTC, is a synthetic nucleoside analogue used as an active pharmaceutical ingredient in antiviral therapy.
Where is Emtricitabine used?
- HIV and hepatitis B treatment: reverse transcriptase inhibitor that blocks viral replication
- Fixed-dose combination antiretroviral tablets: primary API co-formulated with tenofovir, efavirenz, or integrase inhibitors for once-daily HIV treatment
- Pre-exposure prophylaxis formulations for HIV prevention
- Pharmaceutical manufacturing: key intermediate for branded and generic antiretroviral drug products
- Research and contract development: bioequivalence studies and analytical reference standard preparation
- It is a white to off-white crystalline powder.
Commercial specifications
- Pharmaceutical-grade quality aligned with USP and Ph. Eur. monograph specifications
- Bulk API quantities and smaller research-grade lots
Other Names (Synonyms)
Coviracil|BW-524W91|524W91|5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine|2'-deoxy-5-fluoro-3'thiacytidine|(−)-β-2',3'-dideoxy-5-fluoro-3'-thiacytidine|(−)-FTC|(−)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine|FTC
What are the physical properties of Emtricitabine?
Melting Point 136-140°C
Boiling Point 443.3±55.0 °C(Predicted)
Density 1.82±0.1 g/cm3(Predicted)
Appearance White to Off-White Crystalline Solid
Color White to Pale Yellow
Form Solid
Which trade and regulatory codes apply to Emtricitabine?
HS Code 2934990002
Storage Class 11 - Combustible Solids
WGK (Germany) 1