Fexofenadine hydrochloride

Fexofenadine hydrochloride (CAS 153439-40-8), marketed under the brand name Allegra, is a second-generation antihistamine active pharmaceutical ingredient used in the manufacture of prescription and OTC allergy relief products.

Where is Fexofenadine hydrochloride used?

• Oral dosage forms: tablets and capsules for seasonal allergic rhinitis and chronic idiopathic urticaria
• Branded and private-label antihistamine products from contract manufacturers and generic drug producers
• Pediatric oral suspension development
• Topical formulations targeting skin hypersensitivity and allergic dermatitis responses
• It targets peripheral H1 receptors without significant CNS penetration.

Commercial specifications

• USP, BP, and Ph. Eur. compendial grades
• Micronized grades for dissolution and bioavailability targets
• Particle size and solubility profiles influence grade selection for liquid applications
• Bulk quantities for large scale pharmaceutical manufacturing