Lidocaine hydrochloride

Lidocaine hydrochloride (CAS 73-78-9) is the water-soluble salt form of lidocaine, the benchmark local anesthetic active used across injectable, topical, and dental pharmaceutical formulations.

It is a regulated active pharmaceutical ingredient (API) sourced by formulators, contract manufacturers, and pharmaceutical importers operating under strict pharmacopoeial standards.

In injectable pharmaceuticals, it is formulated into nerve block and epidural anesthetic solutions, requiring high-purity API meeting injectable-grade specifications for safety and efficacy.

Topical formulations, including creams, gels, patches, and sprays, use it as the primary anesthetic active for pain and itch relief in OTC and prescription products across global markets.

Dental cartridge manufacturers incorporate it into lidocaine-epinephrine combination solutions for procedural anesthesia. In cosmetic products, it appears in formulations targeting minor skin discomfort.

Regulatory classification for these applications varies by market and concentration. Lidocaine hydrochloride is supplied as a white crystalline powder for easy integration into various bases.

It is available in USP, BP, and Ph. Eur. grades to meet injectable and oral pharmaceutical requirements, with technical grade available for non-pharmaceutical applications.

Packaging ranges from kilogram quantities for development and compounding use to bulk drums for commercial manufacturing, ensuring scalability for diverse industrial and medical needs.