Lidocaine hydrochloride
CAS Number
73-78-9
EC Number
200-803-8
What is Lidocaine hydrochloride?
Lidocaine hydrochloride (CAS 73-78-9) is the water-soluble salt form of lidocaine, the benchmark local anesthetic active.
Where is Lidocaine hydrochloride used?
- Injectable pharmaceuticals: nerve block and epidural anesthetic solutions
- Topical creams, gels, patches and sprays: primary anesthetic active for pain and itch relief
- Dental cartridges: lidocaine-epinephrine combination solutions for procedural anesthesia
- Cosmetic products: formulations targeting minor skin discomfort
- It is a regulated active pharmaceutical ingredient (API) for formulators, contract manufacturers and pharmaceutical importers.
Good to know: Regulatory classification varies by market and concentration. Injectable-grade API must meet high-purity specifications.
Commercial specifications
- Packaging from kilogram quantities for development and compounding to bulk drums for commercial manufacturing
Other Names (Synonyms)
omega-Diethylamino-2,6-dimethylacetanilide hydrochloride|alpha-Diethylamino-2,6-acetoxylidine hydrochloride|2-Diethylamino-2',6'-acetoxylidide hydrochloride|lidocaine hydrochloride anhydrous|LIDOCAINE HCL|Lignocaine hydrochloride|Xylocaine Viscous|Laryng-O-jet
What are the physical properties of Lidocaine hydrochloride?
Melting Point 77-78 °C
Appearance White to Off-White Solid
Color White to off-white
Form Solid
Water Solubility Water : ≥ 36 mg/mL (132.94 mM)
Log P 2.359 (est)
How is Lidocaine hydrochloride classified and handled safely? Learn More
Danger
GHS06· Toxic GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H301 Toxic if swallowed
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary Statements
P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.