Procaine

Procaine (CAS 59-46-1), also known commercially as Vitamin H3, is a synthetic local anesthetic active pharmaceutical ingredient with a long history in medical and pharmaceutical manufacturing.

Where is Procaine used?

• Pharmaceutical manufacturing: active ingredient in injectable local anesthetic formulations
• Dental and minor surgical procedures: nerve-blocking agent that temporarily inhibits pain signal transmission
• Synthesis of next-generation anesthetic derivatives and pharmaceutical intermediates: starting material or reference compound
• Compounding pharmacies prepare specialized injectable solutions where longer-acting agents are contraindicated.
• Research and analytical laboratories procure it as a reference standard for method validation and quality control testing of anesthetic formulations.

Good to know: The hydrochloride salt is the predominant commercial form due to its water solubility. Standard grades include USP, BP, and Ph. Eur., supporting use in regulated manufacturing.

Commercial specifications

• Bulk quantities for industrial API production; smaller quantities for laboratory and compounding applications