Chlorhexidine acetate

CAS Number
56-95-1
EC Number
200-302-4
Chemical Formula
C22H30Cl2N10.2C2H4O2
Molecular Weight
625.5 g/mol

Description

Chlorhexidine acetate (CAS 56-95-1), also known as chlorhexidine diacetate and sold under the trade name Hibitane diacetate, is a broad-spectrum antimicrobial salt used across pharmaceutical, personal care, and healthcare manufacturing. It delivers reliable bactericidal and fungicidal activity at low concentrations, making it a preferred active ingredient where microbial control is a critical formulation requirement for industrial and medical applications.

In pharmaceutical manufacturing, it is incorporated into topical antiseptic solutions, wound care products, and surgical scrubs where regulatory-grade antimicrobial performance is required for safety and efficacy. Personal care formulators use it as a preservative and active biocide in mouthwashes, skin cleansers, and intimate hygiene products. Water treatment applications include its use as a biocide for controlling microbial growth.

It also functions as a preservative in ophthalmic preparations and contact lens solutions, where low irritation potential at effective concentrations is a key formulation consideration for manufacturers. Chlorhexidine acetate is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications including BP and Ph. Eur., which are the standard grades demanded.

These quality standards ensure the material is suitable for healthcare and regulated personal care markets. Technical-grade material is also available for industrial biocide applications and process water treatment.

Other Names (Synonyms)

Chlorhexidine diacetate|Hibitane diacetate|Chlorohexidine diacetate|10,040 Diacetate|Chlorhexidini diacetas|5908ZUF22Y|Biguanide, 1,1′-hexamethylenebis[5-(p-chlorophenyl)-, diacetate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 154-155 °C
Appearance White or almost white, microcrystalline powder
Color White to Almost white
Form neat
Water Solubility 1.9 g/100 mL (20 ºC)
Log P 4.931 (est)

Documentation

Safety & Handling Learn More

Danger
GHS06· Toxic GHS07· Irritant GHS09· Environmental Hazard GHS05· Corrosive GHS08· Health Hazard

Hazard Statements

H301 Toxic if swallowed
H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H318 Causes serious eye damage

Precautionary Statements

P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.

Trade & Regulatory

HS Code 2925294500
UN Number 3077
ADR Class 9
Packing Group III
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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